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EC number: 202-327-6 | CAS number: 94-36-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
The acute effects of dibenzoyl peroxide on earthworms (Eisenia foetida foetida) were determined according to the OECD Guideline 207 (1984) and GLP requirements (Chastenet, 2015). The valid experiment concluded that 14d-LC50 was higher than 1000 mg a.i./kg dw.
A valid experiment has also been performed in order to determine the effects of dibenzoyl peroxide on nitrogen transformation according to OECD guideline 216 and GLP requirements (Bangert, 2015). The objective was to determine the effects of the substance on soil microbial activity. The results were 28d-EC10 = 1000 mg a.i./kg dw and 28d-EC50 = 2300 mg a.i./kg dw.
Dibenzoyl peroxide is considered as a soil hazard category 2 substance (Table R.7.11 -2 of Chaper R.7c, Version 2.0 November 2014). Indeed, the substance has a Log Kow < 5 and is readily biodegradable, confirming that there is no indication for high adsorption or high persistence in soil. Nevertheless, EC/LC50 below 1 mg/L were determined in acute toxicity tests, leading to the conclusion that the substance is very toxic to aquatic organisms.
For a soil hazard category 2 substance, a risk characterisation ratio (RCR) based on Equilibrium Partitioning Method (EPM) should be calculated, together with a confirmatory short-term soil toxicity testing.
PNEC soil calculated from EPM = 0.0025 mg/kg soil dw. The following formula has been applied : PNEC soil = (Ksoil water / RHOsoil) x PNECaqua x 1000 With: RHOsoil = bulk density of wet soil = 1700 kg/m3, using a Koc value of 6310, a vapour pressure of 0.009 Pa and a PNEC freshwater of 0.02 µg/L. Finally, a conversion factor of 1.13 is used for converting wet to dry weight.
From the result obtained on acute toxicity to earthworms, an assessment factor of 1000 is applied on 14d-LC50. Therefore, PNEC soil calculated from the OECD 207 test = 1 mg/kg soil dw.
In addition, a long-term toxicity test on microorganisms is available and an assessment factor of 100 can be applied on the 28d-EC10 value. PNEC soil calculated from OECD 216 test = 10 mg/kg soil dw.
The lowest PNEC soil is derived from EPM and thus it was used to calculate the RCR for the soil compartment. No risks (PEC/PNEC < 1) has been identified. In accordance with the Integrated testing strategy for terrestrial toxicity testing (Figure R.7.11 -3 of Chapter R.7c, Version 2.0 November 2014), there is no need to perform additional short-term or long-term studies on soil organisms.
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