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Diss Factsheets
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EC number: 920-360-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 22-Aug-1994 to 23-Sep-1994
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: This study was given a reliability of 1, because it followed an OECD standard guideline, which describes a procedure specifically designed to evaluate this endpoint, and the results were reviewed for reliability and assessed as valid.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- no
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- Inoculum used as the source of the microorganisms was an aliquot of fresh activated sludge from a domestic wastewater treatment facility in New Jersey, USA.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- ca. 35 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Activated sludge and test medium were combined prior to test substance addition. Test medium consisted of glass-distilled water and mineral salts (Phosphate buffer, Ferric chloride, Magnesium sulfate, Calcium chloride). Test vessels were 1L glass flasks located in a waterbath and electronically monitored for oxygen consumption. Test temperature was 21 +/- 1 Deg C. All test vessels were stirred constantly for 28 days using magnetic stir bars and plates.
Test material was tested in triplicate, controls and blanks were tested in duplicate. The amount of oxygen consumed by microorganisms from the oxidation of the test material was continuously monitored by an automated respirometer during the 28-day test period. Test material concentration was 35mg/L. Sodium benzoate (positive control) concentration was 50mg/L. All test vessels were stirred constantly for 28 days using magnetic stir bars and plates. - Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (O2 consumption)
- Value:
- 15.4
- Sampling time:
- 4 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 50.4
- Sampling time:
- 11 d
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 60.7
- St. dev.:
- 2.77
- Sampling time:
- 28 d
- Details on results:
- Test material was readily biodegradable, but failed the 10-day window. The biodegradation half-life was <2 weeks. On day 28, 60.7% degradation of the test substance was observed. 10% biodegradation was achieved on approximately day 4, 50% on approximately day 11, and 60% on day 27. By day 3, >60% biodegradation of the positive control was observed. No excursions from the protocol were noted.
The study was extended to Day 31, where the test substance achieved a mean percent biodegradation of 61.5%. - Results with reference substance:
- Sodium benzoate, the positive control, achieved 99.0% degradation after 14 days, and therefore this test may be considered valid. On Day 28 of the study, the mean percent degradation of the positive control was 88.7%.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable, but failing 10-day window
- Conclusions:
- Hydrocarbons, C14 -C18, n-alkanes, isoalkanes, cyclics, aromatics (2 -30%), a multi-component substance, biodegraded to an extent of 61% after 28 days. The data support characterizing the test substance as rapidly biodegradable, readily biodegradable, not expected to persist in the environment under aerobic conditions. Although it did not meet the 10 -day window requirement, it is characterized as readily biodegradable because the criteria is not applied to multi-component substances when assessing their ready biodegradability.
- Executive summary:
Hydrocarbons, C14-C18, n-alkanes, isoalkanes, cyclics, aromatics (2 -30%), a multi-component substance, biodegraded to an extent of 61% after 28 days. The data support characterizing the test substance as rapidly biodegradable, readily biodegradable, not expected to persist in the environment under aerobic conditions. Although it did not meet the 10 -day window requirement, it is characterized as readily biodegradable because the criteria is not applied to multi-component substances when assessing their ready biodegradability.
Reference
Biodegradation was based on oxygen consumption and the theoretical oxygen demand of the test material as calculated using results of an elemental analysis of the test material.
|
% Degradation* |
Mean % Degradation |
Sample |
(day 28) |
(day 28) |
Test Material |
66.8, 56.2, 59.1 |
60.7 |
Na Benzoate |
89.9, 87.5 |
88.7 |
* replicate data
Description of key information
There is data available for this substance, which is presented in the dossier.
Based on the available data, this substance is considered readily biodegradable. Key information is summarised below:
Hydrocarbons, C14-C18, n-alkanes, isoalkanes, cylcics, aromatics (2-30%) biodegraded to an extent of 61% after 28 days. Although it did not meet the 10 -day window requirement, it is characterized as readily biodegradable because the criteria is not applied to multi-component substances when assessing their ready biodegradability.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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