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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
1999
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Only data from review article available

Data source

Reference
Reference Type:
review article or handbook
Title:
Lithium Hydroxide
Author:
Kushneva, V.S., and R.B. Gorshkova
Year:
1999
Bibliographic source:
Spravochnik po Toksikologii i Gigienicheskim Normativam (PDK) Potentsial'no Opasnykh Khimicheskikh Veshchestv", page 153 (1999)

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Only data from review article available. No guideline or method indicated.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Lithium hydroxide
EC Number:
215-183-4
EC Name:
Lithium hydroxide
Cas Number:
1310-65-2
Molecular formula:
HLiO
IUPAC Name:
lithium hydroxide

Test animals

Species:
mouse

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
363 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
Category 4 based on GHS criteria
Conclusions:
According to the handbook-data, the LD50 of lithium hydroxide is 336.0 +/- 7.8 mg/kg bw after oral administration to mice.
Executive summary:

According to the handbook-data, the LD50 of lithium hydroxide is 336.0 +/- 7.8 mg/kg bw after oral administration to mice.