Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Acute toxicity, oral:
LD50 > 2000 mg/kg bw for rat

Key value for chemical safety assessment

Additional information

Acute toxicity, oral:

LD50 > 2000 mg/kg bw for rat

Justification for classification or non-classification

Acute toxicity

Rats were treated with disodium titanate by single oral gavage administration at a dosage of 2000 mg/kg body weight.

During the course of the study, no intercurrent deaths occurred, no clinical signs were observed, no macroscopic findings were recorded at necropsy. Also, the body weight of the animals was within the range commonly recorded for this strain and age.

LD50 oral, rat > 2000 mg/kg bw

The classification criteria acc. to regulation (EC) 1272/2008 as acutely toxic are not met since the LD50 is above 2000 mg/kg body-weight, hence no classification is required.