Isobutyric acid

Henry's Law constant

Link to relevant study record(s)

Reference

Endpoint:

Henry's law constant

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Acceptable, well-documented publication which meets basic scientific principles

Qualifier:

no guideline available

Principles of method if other than guideline:

Determination of thermodynamic Henry's law constants by equilibrium partial pressure measurements over aqueous solutions at 298.15 K

GLP compliance:

no

H:

1 130 other: mol/atm kg

Temp.:

25 °C

The reported value is equivalent to 8.85E-7 atm m³/mol.

Conclusions:

For isobutyric acid, an experimetal HLC of 8.84E-7 atm m³/mol was determined in a study according to accepted scientific principles

Executive summary:

For isobutyric acid, a Henry's law constant of 8.85E-7 atm m³/mol was determined in a study using equilibrium partial pressure measurements over aqueous solutions at 298.15 (25°C).

Description of key information

measured HLC (25°C) = 8.85E-7atm*m3/mol (0.08967 Pa*m3/mol) (method: equilibrium partial pressure measurements over aqueous solutions)

Key value for chemical safety assessment

Henry's law constant (H) (in Pa m³/mol):

0.09

at the temperature of:

20 °C

Additional information

For isobutyric acid, a Henry's law constant of 8.85E-7 atm m³/mol was determined in a study using equilibrium partial pressure measurements over aqueous solutions at 298.15 K (25°C) (Khan, 1992).

 

A calculated Henry's law constant of 9.65E-007 atm*m3/mol (bond contribution method) and of 9.09E-007 atm*m3/mol (group contribution method) was obtained using the program HENRYWIN v 3.2 (Part of US EPA EPI Suite v4.00) (ECT, 2009). Measured and calculated HLC match satisfactorily.

 

Isobutyric acid volatilizes only to a low degree from water.