Registration Dossier
Registration Dossier
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EC number: 225-768-6 | CAS number: 5064-31-3
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
BASF (1999) provided results of 72 hr EC50 of >91.5 mg/L (biomass and growth) and 72 hr NOEC of 1.43 mg/L for Scenedesmus subspicatus. The study was performed according to OECD 201 and GLP.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 91.5 mg/L
- EC10 or NOEC for freshwater algae:
- 1.43 mg/L
Additional information
A summary of toxicity to aquatic algae is presented in the table below:
| Guideline | Species | Effect Concentration | Reference | Reliability |
| / | Several | No effects concentration reported. NTA has no toxic effects on the growth of algae. |
Brouwer and Terpstra (1994) | 4- secondary literature |
| OECD 201 | Scenedesmus subspicatus | 72hr EC10 = 22.8 mg/L (growth), 74.8 mg/L (biomass)72hr NOEC = 1.43 mg/L, 1.56 mg/L (conc. not meas.)72 hr EC50 = >91.5 mg/L (biomass and growth) | BASF (1999) | 1 -reliable without restrictions (GLP) |
| Equivalent to OECD 201 | Scenedesmus capricornutum; Chlorella vulgaris; Scenedesmus subspicatus | Scenedesmus capricornutum: LOEC = 5 -50 mg/L (dependent on growth medium); Chlorella vulgaris: LOEC = 5 -80 mg/L (dependent on growth medium); Scenedesmus subspicatus: LOEC = 5 -80 mg/L (dependent on growth medium) | Millington et al (1988) | 3 -not reliable |
| Equivalent to OECD 201 | Navicula seminulum | 5-d EC50: (flowthrough, soft water) = 143 mg/L(static, soft water) = 198 mg/L(flowthrough, hard water) = 507 mg/L(static, hard water) = 507 mg/L | Weaver (1967) | 2 - reliable with restrictions |
| Other Guideline: cell multiplication inhibition test | Scenedesmus quadricauda | Test with Nitrilotriacetic acid; 8 day toxicity threshold = 8.3 mg/L NTA | Bringmann & Kuhn (1977) | 3 - unreliable |
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