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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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Physical & Chemical properties

Partition coefficient

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Description of key information

Log Pow = 1.6

Key value for chemical safety assessment

Log Kow (Log Pow):
1.6
at the temperature of:
25 °C

Additional information

The partition coefficient (Log Pow) of prednisolone is 1.6 at 25 °C and at pH of 7.4. The partition coefficient was determined in a way equivalent or similar to OECD test guideline 107 (Lombardo, F. 2000 (a)).

In the same study the Log Pow of 1.83 was obtained from HPLC method. The partition coefficient was determined in a way equivalent or similar to OECD test guideline 117 (Lombardo, F. 2000 (b)).

In an additional study a value of Log Pow of 1.62 was reported. (Exploring QSAR: Volume 1).