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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
0.192 mg/L
Assessment factor:
50
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
2.75 mg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.019 mg/L
Assessment factor:
500
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
580 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
0.155 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
0.015 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
0.035 mg/kg soil dw
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Conclusion on classification

Titanium (4 +)ethanolate is hydrolytically unstable with the half-life of less than 5 minutes determined by OECD 111. In this study, the progress of the hydrolysis was followed by monitoring ethanol (EtOH), the main degradation product of the substance. The other non-hazardous degradation product (hydrated titanium oxide) is insoluble lacking bioavailablity in aquatic environment, and therefore not further considered in CSA.

Because of the rapid hydrolysis of this substance, the intrinsic properties of aquatic toxicity are related to the main degradation product (EtOH) of this substance. The short-term and long-term aquatic toxicity testing was considered scientifically unjustified and the supporting read-across data from the main degradation product (EtOH) was used as a key value in CSA.

The following reliable data is available for environmental classification of titanium (4 +) ethanolate:

Acute Aquatic – hazard class

Short-term toxicity to fish:

·   96-h LC50 (mortality) to Pimephales promelas, 14 200 mg/L based on measured concentrations (read-across from EtOH; Brooke et al. 1984)

Short term and long-term toxicity to invertebrates:

·   48-hour LC50 (immobilisation) to Ceriodaphnia dubia, 5 012 mg /l based on nominal concentrations. (read-across from EtOH; Takahashi et al. 1987)

·   10-d NOEC (reproduction) to Ceriodaphnia dubia, 9.6 mg/l based on nominal concentrations. (read-across from EtOH; Cowgill & Milazzo 1991)

Toxicity to algae:

·   The 72h-EC10 (growth rate) to Chlorella vulgaris, 11.5 mg /l based on measured nominal (OECD 201; read-across from EtOH; El Jay 1996)

·   The 72h-EC50 (growth rate) to Chlorella vulgaris, 275 mg /l based on measured nominal (OECD 201; read-across from EtOH ; El Jay 1996)

Toxicity to micro-organisms:

·        LC50 (mortality) to Paramaecium caudatum; 5 800 mg/l based on nominal concentrations (read-across from EtOH; Rajini et al. 1989)

Conclusion: No acute aquatic toxicity as the lowest of the available toxicity value is > 100 mg/l.

Chronic – hazard class:

Degradation: 

Abiotic degradation (hydrolysis): Hydrolytically unstable, Half-life less than 5 minutes (OECD 111)

Main organic decomposition product (EtOH) is non-toxic to aquatic environment and readily biodegradable (> 90 % at 15-d biodegradation, Price et al. 1974). 

Conclusion: rapidly degradable. 

Bioaccumulation:

Log Kow: -0.3 for the main degradation product (EtOH). Not possible to determine for the target substance because of rapid hydrolysis. 

Conclusion: No chronic aquatic toxicity as the lowest available long-term toxicity value is > 1 mg/l and the short-term toxicity value is > 100 mg/l, substance is rapidly degradable, and the degradation products have low potential for bioconcentration and bioaccumulation. 

Environmental classification:

In accordance with EC Regulation 1272/2008 (CLP):

Not classified as hazardous

In accordance with DSD (Directive 67/548/EEC):

Not classified as hazardous