Registration Dossier
Registration Dossier
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EC number: 200-198-0 | CAS number: 54-21-7
Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
- Justification for type of information:
- Experimental test result performed using standard test guidelines.
- Qualifier:
- according to guideline
- Guideline:
- other: Gravimetric method
- Principles of method if other than guideline:
- Weight of the chemical substance (fat) to dissolve in Organic Solvent to form a homogeneous solution of the solute in the solvent
- GLP compliance:
- no
- Other quality assurance:
- ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
- Key result
- Medium:
- methanol
- Solubility:
- 206 000 mg/L
- Temp.:
- 25 °C
- Remarks on result:
- other: no other details mentioned
- Key result
- Medium:
- other: petroleum ether
- Solubility:
- 1 800 mg/L
- Temp.:
- 25 °C
- Remarks on result:
- other: no other details mentioned
- Conclusions:
- The Solubility of test chemical in various organic solvents is determined as follows, in methanol determined as 206000 mg/L 25 °C and in petroleum ether determined as 1800 mg/L 25 °C.
- Executive summary:
Based on available data from experimental report the Solubility of test chemical in various organic solvents is determined as follows, in methanol determined as 206000 mg/L 25 °C and in petroleum ether determined as 1800 mg/L 25 °C.
Hence on the basis of obtained values the test chemical is considered to be very soluble in methanol and soluble in petroleum ether.
Reference
Description of key information
Based on available data from experimental report the Solubility of test chemical in various organic solvents is determined as follows, in methanol determined as 206000 mg/L 25 degC and in petroleum ether determined as 1800 mg/L 25 degC.
Hence on the basis of obtained values the test chemical is considered to be very soluble in methanol and soluble in petroleum ether.
Key value for chemical safety assessment
- At the temperature of:
- 25 °C
- Solubility in organic solvents at 20°C:
- 206 000 mg/L
Additional information
Based on available data from experimental report the Solubility of test chemical in various organic solvents is determined as follows, in methanol determined as 206000 mg/L 25 degC and in petroleum ether determined as 1800 mg/L 25 degC.
Hence on the basis of obtained values the test chemical is considered to be very soluble in methanol and soluble in petroleum ether.
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