2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone

Toxicity to microorganisms

Administrative data

Endpoint:

activated sludge respiration inhibition testing

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Test was conducted according to OECD 209 and compliant with GLP.

Data source

Reference

Reference Type:

other: Body responsible for the test

Title:

Unnamed

Year:

1990

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test

Deviations:

not specified

GLP compliance:

yes

Test material

Test material information

Constituent 1

Reference substance name:

2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone

EC Number:

404-360-3

EC Name:

2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone

Cas Number:

119313-12-1

Molecular formula:

C23H20N2O2

IUPAC Name:

2-benzyl-2-(dimethylamino)-1-[4-(morpholin-4-yl)phenyl]butan-1-one

Test organisms

Test organisms (species):

activated sludge

Study design

Test type:

other: aerobic

Total exposure duration:

0.5 h

Results and discussion

Effect concentrations

Duration:

30 min

Dose descriptor:

IC50

Effect conc.:

> 5.9 mg/L

Conc. based on:

test mat.

Any other information on results incl. tables

NOEC (mg/L): 30 minutes: supersaturated solution of the substance was generated using 50 mg in 500 ml. This is well in excess of solubility and would have resulted in a maximum dissolved concentration of 5.9 mg/L (but is likely to have been considerably lower by comparison with the concentrations achieved in the other tests carried out on the substance). No effects were seen on respiration of the sludge at the maximum attainable concentration.