Registration Dossier
Registration Dossier
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EC number: 219-147-9 | CAS number: 2373-38-8
Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2012
- Reliability:
- 1 (reliable without restriction)
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 105
- GLP compliance:
- no
- Medium:
- n-octanol
- Solubility:
- > 500 g/L
- Temp.:
- 20 °C
- Test substance stable:
- yes
- Executive summary:
In the non-GLP Kllimisch 1 study from Frischmann (2012) the octanol solubility of Sodium di(1.3-dimethylbutyl) sulfosuccinate was determined following the method as outlined in the OECD 105. Instead of water, octanol was used. The octanol solubility at 20°C was determined to be > 500 g/L.
This value is considered relevant an reliable for the risk assessment.
Reference
The following aliquots of Sodium di(1.3-dimethylbutyl) sulfosuccinate were added to 2 g of n-octanol and stirred slowly for ten minutes.
Aliquot/ Weighed sample [g] |
Observation |
0.1 |
Clear solution |
0.5 |
Clear solution |
1.0 |
Clear solution, increasing viscosity |
2.0 |
Jelly like, highly viscous |
With 2 g test item being added to 2 g n-octanol a gel with approximately 3.65 g was formed (2 g test item, about 1.65 g n-octanol. This is equivalent to 55% (w/w) of the test item in the gel. As the density of the solution/gel increased it can be concluded that the octanol solubility is about 550 g/L in the gel. Since gel formation is a continuous process, the water solubility is reported as > 500 g/L.
Description of key information
octanol solubility at 20°C > 500 g/L.
Key value for chemical safety assessment
Additional information
In the non-GLP Kllimisch 1 study from Frischmann (2012) the octanol solubility of Sodium di(1.3-dimethylbutyl) sulfosuccinate was determined following the method as outlined in the OECD 105. Instead of water, octanol was used. The octanol solubility at 20°C was determined to be > 500 g/L.
This value is considered relevant an reliable for the risk assessment.
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