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Diss Factsheets
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EC number: 603-923-2 | CAS number: 135590-91-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
The environmental profile of the substance is well defined. Short-term and long-term tests with species of three trophic levels are available for the parent substance and different metabolites of the parent.
The effect concentrations recorded for the parent substance are generally lower compared to the effect values determined for the different metabolites.
Fish turned out to be the most sensitive organisms group in acute and chronic toxicity testing. The LC50 (96 h) determined in a short-term study according to OECD guideline 203 on mirror carp was 2.4 mg/L (nominal). The effect concentrations determined for aquatic invertebrates were in the same order of magnitude. For Daphnia magna an EC50 (48 h) of 5.9 mg/L (measured) was determined. The EC50 (96 h) based on the growth rate of green algae was 10.71 mg/L based on the measured substance concentration. The related NOEC (96 h) was 2.86 mg/L (measured). A 28-day Juvenile Fish Growth Test according to OECD 215, conducted under flow-through conditions, determined a NOEC (28 d) of 0.1 mg/L for chronic toxicity to fish. In the key long-term study on Daphnia magna a NOEC (21 d) of 0.32 mg/L (nominal) was determined based on reproduction and offspring survival.
The 3-h EC50 of the test substance for respiratory inhibition of activated sludge was > 1000 mg/L, the limit dose for this type of study. This indicates a low toxicity of the substance to sludge microorganisms and inhibition of the degradation activity of activated sludge is not anticipated.
In the natural environment (soil, water) the substance is quickly metabolized. Degradation takes place via successive hydrolysis at one of the two ester functions of the parent molecule, followed by decarboxylation and aromatization as the major steps of degradation, therefore a long term exposure of the aquatic environment is not expected.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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