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REACH

Lithium dodecyl sulphate

EC number: 218-058-2 | CAS number: 2044-56-6

Life Cycle description
Uses advised against

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

96h LC50 (Pimephales promelas) = 29 mg/L (measured concentration, freshwater, OECD 203)
96h LC50 (Cyprinodon variegates) = 4.1 mg/L (measured concentration, marine water, ASTM E-35 1980)

Key value for chemical safety assessment

Fresh water fish

Effect concentration:: 29 mg/L

Marine water fish

Effect concentration:: 4.1 mg/L

Additional information

Since no reliable short term toxicity studies on fish are available for C12AS Li (CAS 2044-56-6), in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 a read-across to another structurally related category member was conducted. The short-term toxic effects are assessed based on read-across data from another C12 homologue, C12AS Na (CAS 151-21-3). Since the toxicity of alkyl sulfates is dependent on the carbon chain length, it is expected that the toxic effects are comparable for all the C12 homologues and the influence of the counter ion can be neglected.

Toxic effects of CAS 151-21-3 to fathead minnow (Pimephales promelas) were studied in a non-GLP test performed according to OECD 203 guideline (Rawlings 2004). Fish were exposed in a flow-through system to five test concentrations up to 48 mg/L of nominal concentration, corresponding to 40 mg/L of measured concentration. Mortality of fish was evaluated every 24 hours. The test substance was determined to have the 96-hour LC50 value of 29 mg/L (measured concentration). Moreover, the short term effects of CAS 151-21-3 were studied on the marine sheepshead minnow Cyprinodon variegatus (Roberts et al. 1982). This non-GLP test was performed according to ASTM E-35 (1980) method. Fish were exposed to five test concentrations in brackish water (salinity 10 ‰) under static conditions. The 96h LC50 value of 4.1 mg/L was determined (measured concentration).

Due to structural and property similarities with the tested category member, it can be concluded that the above results also apply to C12AS Li (CAS 2044-56-6).

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