Registration Dossier
Registration Dossier
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EC number: 416-740-6 | CAS number: -
Toxicity to terrestrial plants
Administrative data
Link to relevant study record(s)
Description of key information
Toxicity to terrestrial plants - read-across data (3 key studies in ryegrass, radish and soybean for DEHT surrogate)
Key value for chemical safety assessment
Additional information
No terrestrial plant toxicity studies have been carried out on the submission substance (CAS No. 162030-42-4). However, short-term terrestrial plant toxicity studies have been reported for di-2-ethylhexyl terephthalate (DEHT) (CAS No. 6422-86-2) which can provide some useful read-across assessment for the submission substance which is structurally related to DEHT in that it is a di-C13-alkyl terephthalate analog.
The toxicity of the read-across surrogate, di-2-ethylhexyl terephthalate (DEHT) (CAS No. 6422-86-2), as measured by effects on the seedling growth to ryegrass, radish and soybean was evaluated in a 14-day terrestrial plant toxicity test (ABC Labs, 1986b). Results in table below indicated that DEHT had no biologically deleterious effects on the seedling growth of ryegrass (Lolium perenne), radish (Raphanus sativus) and soybean (Glycine max) in the 14-day toxicity tests. Collectively, these findings indicate that the DEHT does not cause acute toxicity to terrestrial plants at the highest loading tested (i.e., 1500 µg/L) and at concentrations that exceeded the aqueous solubility of the test material (400 µg/L).
Based on the read-across plant toxicity data for DEHT, the submission terephthalate substance, CAS No. 162030-42 -4, would not be expected to cause toxicity or adverse effects to terrestrial plants such as ryegrass, radish or soybean.
Although no plant toxicity data are available for the submission substance, EC No. 416-740-6, there are sufficient data reported for structurally analogous di-2-ethylhexyl terephthalate (CAS No. 6422-86-2) that provide useful read-across assessment. Therefore, based on the read-across for the surrogate DEHT, the submission substance (EC No. 416-740-6) is expected to cause no acute toxicity to terrestrial plants.
Studies are not available to assess the chronic toxicity of the submission substance (EC No. 416-740-6) to plants. However, the submission substance is inherently biodegradable in the environment and it is not expected that terrestrial plants will be exposed significantly to the submission substance in the environment (e.g., soil). As read-across acute plant toxicity data for the structurally related surrogate, di-2-ethylhexyl terephthalate, showed no effects at high exposure concentrations or loadings levels. Read-across acute and chronic toxicity with other terrestrial organisms (e.g., earthworm) showed no effects at the highest exposure loadings, chronic effects to terrestrial plants would not be expected for the submission substance. Hence, the submission substance would not expected to pose a chronic hazard to terrestrial plants at environmentally relevant exposure levels.
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