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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Basing on a category read-across approach, bis[2-[2-(2-butoxyethoxy)ethoxy]ethyl]adipate is neither irritant to the skin nor to the eye.

Key value for chemical safety assessment

Skin irritation / corrosion

Link to relevant study records
Reference
Endpoint:
skin irritation / corrosion, other
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
weight of evidence
Justification for type of information:
Adipic acid diesters category. See attached report.
Remarks on result:
no indication of irritation
Interpretation of results:
GHS criteria not met
Conclusions:
Adipic acid diesters category members showed no to slight dermal irritation in in vivo studies.
Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Link to relevant study records
Reference
Endpoint:
eye irritation, other
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
weight of evidence
Justification for type of information:
Adipic acid diesters category. See attached report.
Remarks on result:
no indication of irritation
Interpretation of results:
GHS criteria not met
Conclusions:
Available data on rabbits indicate that category members are not irritant to the eyes.
Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Justification for classification or non-classification

Basing on the available data, bis[2-[2-(2-butoxyethoxy)ethoxy]ethyl]adipate is classified neither for skin irritation/corrosion nor for serious eye damage/eye irritation according to Regulation (EC) n. 1272/2008.