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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

The 48-h EC50 for Daphnia magna was 2.8 mg/L and the NOEC was 0.84 mg/L.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
2.8 mg/L

Additional information

Daphnia magna were exposed for 48 hours under flow-through conditions to five mean measured concentrations of the substance ranging from 0.39 to 8.7 mg/L in a study performed according to OECD TG 202 [Brougher et al, 2014]. The 48-hour EC50 value was 2.8 mg/L, with a 95% confidence interval of 2.2 to 3.6 mg/L. The slope of the concentration-response curve was 3.5. The no-immobility concentration and the NOEC were 0.84 mg/L.

This result is supported by the results of a study performed according to EPA OTS 797.1300 using a read-across substance, N,N-dimethyldecan-1 -amide, mixture with N,N-dimethyloctan-1 -amide (CAS No. 67359 -57 -3) in which daphnia magna were exposed to the substance for 48 hours under static conditions [Forbis, 1990]. The 48 -hour LC50 was 7.7 mg/L and the NOEC was 4.0 mg/L.