Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 287-401-6 | CAS number: 85507-79-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_toxicological-information.png)
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Study period:
- before 22 February 1971
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Older study conducted prior to the introduction of GLP and OECD test guidelines. Standard methods used but details of methods and results not available. For read-across justification see Section 13.
Data source
Reference
- Reference Type:
- other: Diundecyl phthalate letter summary toxicity data
- Title:
- Unnamed
- Year:
- 1 971
- Report date:
- 1971
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Deviations:
- not specified
- Principles of method if other than guideline:
- Instillation of 0.1 ml of undiluted DUP into rabbit's eye. Observations scored at 1, 24 & 48h after instillation.
Probably FHSA test method used. - GLP compliance:
- no
Test material
- Reference substance name:
- Diundecyl phthalate
- EC Number:
- 222-884-9
- EC Name:
- Diundecyl phthalate
- Cas Number:
- 3648-20-2
- Molecular formula:
- C30H50O4
- IUPAC Name:
- diundecyl benzene-1,2-dicarboxylate
- Details on test material:
- Not reported
Constituent 1
Test animals / tissue source
- Species:
- rabbit
- Details on test animals or tissues and environmental conditions:
- Not reported
Test system
- Vehicle:
- unchanged (no vehicle)
- Controls:
- not specified
- Amount / concentration applied:
- 0.1 ml
- Duration of treatment / exposure:
- Single instillation followed by observation of effects for 48 hours
- Observation period (in vivo):
- 48H
- Number of animals or in vitro replicates:
- 6 based on no. of possible observations for conjunctival irritation
- Details on study design:
- Instillation of 0.1 ml of undiluted DUP in rabbit's eye. Observations scored at 1, 24 & 48h after instillation
Results and discussion
In vivo
Resultsopen allclose all
- Irritation parameter:
- conjunctivae score
- Basis:
- other: all animals
- Time point:
- other: 1h
- Score:
- 4
- Reversibility:
- fully reversible within: 48h
- Remarks on result:
- other: total score possible =110
- Irritation parameter:
- conjunctivae score
- Basis:
- other: all animals
- Time point:
- other: 24h
- Score:
- 3.3
- Reversibility:
- fully reversible within: 48h
- Remarks on result:
- other: total score possible =110
- Irritation parameter:
- conjunctivae score
- Basis:
- other: all animals
- Time point:
- other: 48
- Score:
- 0
- Reversibility:
- fully reversible
- Remarks:
- within 48h
- Remarks on result:
- other: total score possible = 110
- Irritation parameter:
- cornea opacity score
- Basis:
- other: all animals
- Time point:
- other: 1h
- Score:
- 0
- Max. score:
- 0
- Irritation parameter:
- cornea opacity score
- Basis:
- other: all animals
- Time point:
- other: 24h
- Score:
- 0
- Max. score:
- 0
- Irritation parameter:
- cornea opacity score
- Basis:
- other: all animals
- Time point:
- other: 48h
- Score:
- 0
- Max. score:
- 0
- Irritation parameter:
- iris score
- Basis:
- other: all animals
- Time point:
- other: 1h
- Score:
- 0
- Max. score:
- 0
- Irritation parameter:
- iris score
- Basis:
- other: all animals
- Time point:
- other: 24h
- Score:
- 0
- Max. score:
- 0
- Irritation parameter:
- iris score
- Basis:
- other: all animals
- Time point:
- other: 48h
- Score:
- 0
- Max. score:
- 0
- Irritant / corrosive response data:
- minimal conjunctival irritation with a score of 4 out of a possible 110
- Other effects:
- Not reported
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: expert judgment
- Conclusions:
- Slight conjuctival irritation observed following exposure. Recovery within 48 hours
- Executive summary:
Slight conjuctival irritation observed following exposure. Recovery within 48 hours.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
![ECHA](/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/echa_logo.png)