Registration Dossier
Registration Dossier
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EC number: 245-152-0 | CAS number: 22673-19-4
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The following study was provided to fulfil the endpoint toxicity to aquatic algae and cyanobacteria:
Vryenhoef (2003). ALGAL INHIBITION TEST. Testing laboratory: SafePharm Laboratories Ltd, P. O. Box 45, Derby, DE1 2BT, United Kingdom. Report no.: 1194/033. Owner company: Nitto Kasei Co., Ltd. Report date: 2003-11-05.
In an Inhibition to algae study (Vryenhoef, 2003) the 72 hour EC50 was determined to be >2.0 mg/l for both growth rate and biomass. The 72 hour NOEC was determined to be 2.0 mg/l.
From the available data it is clear that neither the growth (r) or the biomass (b) of Scenedesmus subspicatus (CCAP 276/20) were affected by the presence of the test material over the 72-Hour exposure period.
Key value for chemical safety assessment
Additional information
The key study, Vyrenhoef (2003), was conducted to GLP and in line with a recognised guideline (OECD Guideline No 201 (1984) "Alga, Growth Inhibition Test" referenced as EU Method C.3)and has been allocated a Klimisch score of 1. The study is considered to be the key study for this endpoint. The 72 hour EC50 was determined to be >2.0 mg/l for both growth rate and biomass. The 72 hour NOEC was determined to be 2.0 mg/l.
Key value for chemical safety assessment
EC50/LC50 for freshwater algae: >2mg/L
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