Registration Dossier
Registration Dossier
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EC number: 407-870-4 | CAS number: 97384-48-0 CITROWANIL B
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
The experimental design was performed according to the method of B. Magnusson and A.M. Kligman (OECD / EEC-guidelines).
To test the sensitising properties of the compound 20 test- and 20 control-animals (guinea-pigs) were treated with 10 % of the test compound during the induction phases (intradermal and dermal) and with 1 % for the challenge (dermal) using Freund's Complet Adjuvant (FCA) to intensify the immunological reaction.
Any signs of erythema and edema were recorded 24 h and 48 h after the challenge.
According to the method of B. Magnusson and A.M. Kligman (OECD / EEC-guidelines), the compound "CITROWANIL B" is considered not to cause any hypersensitivity in guinea-pigs.
Migrated from Short description of key information:
Citrowanil B does not have skin sensitisation properties.
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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