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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: 4e: Documentation insufficient for assessment

Data source

Reference
Reference Type:
review article or handbook
Title:
No information
Author:
Marhold, J.
Year:
1986
Bibliographic source:
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, Pg. 1071,1986

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Standard Draize test
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
4-chlorobenzenesulphonyl chloride
EC Number:
202-685-3
EC Name:
4-chlorobenzenesulphonyl chloride
Cas Number:
98-60-2
Molecular formula:
C6H4Cl2O2S
IUPAC Name:
4-chlorobenzenesulphonyl chloride

Test animals / tissue source

Species:
rabbit

Test system

Duration of treatment / exposure:
DOSE/DURATION : 50 µg/24h
Details on study design:
Administration into the eye

Results and discussion

Applicant's summary and conclusion

Interpretation of results:
other: severely irritant
Conclusions:
The substance is a severe eye irritant.