Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 412-720-6 | CAS number: 156653-67-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Study period:
- 17 October 2001 to 14 November 2001
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Study conducted to EU & OECD test guidance in compliance with GLP. This study is read across to the structural analogue Reaktiv-Gelb F-97494, which is considered to be structurally equivalent to the substance to be registered. Details of structure are detailed below under "illustrations"
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 001
- Report date:
- 2001
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-D (Determination of the "Ready" Biodegradability - Manometric Respirometry Test)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Details on test material:
- See below
Constituent 1
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
PHYSICO-CHEMICAL PROPERTIES
- Melting point: > 300 deg C
- Boiling point: Not measured
- Vapour pressure: < 10E-05 hPa
- Water solubility (under test conditions): 108 g/l
- Solubility in organic solvents: Not measured.
- log Pow: < -4.9
- Adsorption characteristics:
- Toxicity to microorganisms: EC50 > 10000 mg/l
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- Type: mixed population of aquatic micro organisms(activated sludge)
Origin: aeration tank of a waste water plant treating predominantly domestic sewage (Klaranlage Odenthal)
Date of collection: 2001-10-15
Pre-treatment: none
Concentration of inoculums: 30mg/l SS - Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Pretreatment of the test substance: 25 mg test substance were weighed out on aluminium foil. This substance inclusive the aluminium foil was added to the test vessels to give a test concentration of 100 mg/l test substance.
Reference compound: Sodium benzoate with a purity of 99 % was used as reference compound.
Exposure conditions
Test volume: 250 ml
Test apparatus: Voitli Sapromat
Mixing: 1 magnetic stirrer per test vessel
Incubation time: 28 days
Incubation temperature: 20 ± 1°C
Reference substance
- Reference substance:
- other: Sodium benzonate
Results and discussion
- Preliminary study:
- Not applicable
- Test performance:
- The test substance and reference substance performed within the accepted parameters specified by the guideline.
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- 8
- Sampling time:
- 28 d
- Details on results:
- All validity criteria of the test method were met:
The difference of extremes of replicate values of the removal of test chemical at the end of the test is less than 20 %.
The oxygen uptake of the inoculum blank < 60 mg/l.
The pH - 6.5 - 8.5 in the test vessels at the end of the test (if degradation is less than 60 %).
Oxygen uptake by nitrification has been determined. The oxygen consumed by nitrification was 6 mg/l. This oxygen consumption by nitrification has been substracted from the respective 28 days measurements of the test substance.
BOD5 / COD results
BOD5 / COD
- Parameter:
- BOD5
- Value:
- 915 mg O2/g test mat.
- Results with reference substance:
- The reference compound has reached the level for ready biodegradabilily by 14 days. No toxicity of the test substance has been observed in the toxicity control.
Any other information on results incl. tables
Test substance |
|||||||||||
Time (days) |
|
2 |
6 |
8 |
12 |
14 |
16 |
20 |
22 |
26 |
28 |
Corrected BOD |
a1 |
1 |
3 |
3 |
6 |
6 |
5 |
6 |
9 |
11 |
6 |
Test substance (a-bm) |
a2 |
2 |
4 |
5 |
7 |
7 |
8 |
8 |
10 |
12 |
7 |
[mg O2/l] |
a3 |
3 |
5 |
6 |
7 |
8 |
8 |
9 |
11 |
13 |
8 |
% degradation |
a1 |
1 |
3 |
3 |
7 |
7 |
5 |
7 |
10 |
12 |
7 |
|
a2 |
2 |
4 |
5 |
8 |
8 |
9 |
9 |
11 |
13 |
8 |
|
a3 |
3 |
5 |
7 |
8 |
9 |
9 |
10 |
12 |
14 |
9 |
% degradation, mean |
|
2 |
4 |
5 |
8 |
8 |
8 |
9 |
11 |
13 |
8 |
Comments: pH of the test vessels at the end of the test:
a1: pH = 7.5
a2: pH = 7.5
a3: pH = 7.5
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- Within 28 days, a degradation of 8 % was determined tor Reaktivgelb F97-494.
Reaktivgelb F97-494 has to be classified as "Not Readily Biodegradable". - Executive summary:
A study was performed to assess the ready biodegradabilily of Reaktivgelb F97-494.
The study was conducted in accordance with the Council Directive 92/69/EEC Method C.4-D "Manometric Respirometry Test". This test method is in all essential parts identical with OECD Guideline 301 F. Study performed in accordance with the Principles of Good Laboratory Practice (GLP).
A solution ofReaktivgelb F97-494 in a mineral medium was inoculated and incubated for 28 d under aerobic conditions. During this period the ready biodegradability is determined.
Reaktivgelb F97-494showed:
2 % degradation after 2 days.
4 % degradation after 6 days.
5 % degradation after 8 days.
8 % degradation after 12 days.
8 % degradation after 14 days.
8 % degradation after 16 days.
9 % degradation after 20 days.
11 % degradation after 22 days.
13 % degradation after 26 days.
8 % degradation after 28 days
Therefore the test substance, by analogy of read across has to be classified as "Not Readily Biodegradable".
The reference compound showed 90 % degradation alter 14 days.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Although ECHA is providing a lot of online material in your language, part of this page is only in English. More about ECHA’s multilingual practice.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
the-echa-website-uses-cookies
find-out-more-on how-we-use-cookies