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EC number: 931-745-8 | CAS number: 1335203-21-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 10 µg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.2 µg/L
- Assessment factor:
- 500
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 5.64 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 503 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 10.1 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 101 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Ecotoxicity studies with Oleic-acid based IQAC, DMS quaternised show acute toxicity values < 1 mg/L for aquatic invertebrates and algae.
Short-term toxicity to aquatic organisms
Fish: 96h-LC50 =1.8mg/L for Leuciscus idus (OECD 203)
Crustacea: 48h-EC50 = 105 μg/L forDaphnia magna (OECD 202)
Algae or aquatic plants: 72h-EyC50 = 356 μg/L for Pseudokirchneriella subcapitata (OECD 201)
Long-term toxicity to aquatic organisms
35d NOEC > 100 µg/l for Desmodesmus subspicatus
21d EC10 > 145 µg/l for Daphnia magna with Oleic acid based IQACs, DMS quaternised (CAS-No. 931 -745 -8)
Biodegradation in water: Inherently biodegradable
Bioaccumulation: BCF = 10.7 (read-across from supporting substance partially unsaturated IQAC, DMS quaternised (structural analogue or surrogate)
Ozone layer: Due to the ionic structure and a corresponding negligible vapour pressure of the substance a relevant concentration of the substance in the atmospheric compartment is not expected. Furthermore, according to reaction with OH radicals, the half-life of degradation is short with 3 hours at 25 °C.The registration substance is not expected to reach the atmospheric stratosphere and therefore is not expected to present a danger to the structure and/or the functioning of the stratospheric ozone layer.
The registration substance is classified with regard to environmental effects.
Toxicity towards aquatic micro-organisms is expected to be of no concern for sewage treatment plants. Long-term exposure of aquatic organisms is therefore unlikely.
Bioaccumulation in organisms is considered to be low. Therefore, secondary poisoning through the food chain is of no concern for Oleic-acid based IQAC, DMS quaternised.
Conclusion on classification
Classification and labeling according to GHS Regulation EC No. 1272/2008 (including 2. ATP):
Results from acute tests with fish, Daphnia and algae are available. Long-term studies are available for Daphnia and Algae.
Evaluation of acute aquatic toxicity:
Summary of acute toxicity key values:
Fish: EC50= 1.8 mg/L
Daphnia: EC50 = 0.105 mg/L
Algae: EC50 = 0.330 mg/L
The lowest short-term aquatic toxicity test result is the calculated EC50 (48 h) = 0.105 mg/L for Daphnia magna (OECD 202) (Acute toxicity test).
This value is well below the threshold value for classification of < 1 mg/L; therefore classification for acute aquatic toxicity is required (Aquatic Acute 1, H400).
Evaluation of long-term aquatic toxicity:
Initial considerations:
Oleic-acid based IQAC, DMS quaternised is inherently biodegradable and hydrolysable. The log Kow is ≥ 4 (log Kow of > 5.7), however the experimental determined BCF (10.7) of the read across substance is far below the threshold of < 500.
Summary of long-term toxicity key values:
Daphnia magna: long-term 21 d EC10 > 145µg/L
Algae: long-term 35d NOEC =100 µg/L
For daphnia and algae there is adequate chronic toxicity data available for two trophic levels, classification was assessed based on the criteria outlined in Table 4.1.0(b)(i) substance is not rapidly biodegradable.
Based on the chronic toxicity of 0.1 mg/L and the threshold value≤0.1 mg/L, Category Chronic 1 has to be assigned.
For the other trophic level (fish) only acute toxicity data are available, classification has to be evaluated based on acute data according to the criteria given in Table 4.1.0(b)(iii):
Based on the EC50= 1.8 mg/L for fish and the threshold value of >1 to≤10 mg/L for fish Category Chronic 2 has to be assigned.
Classification for long-term aquatic toxicity has to be the most stringent outcome of both evaluations.
In conclusion oleic-acid based IQAC, DMS quaternised has to be classified as hazardous to the environment with:
Aquatic Acute 1, H400
Aquatic Chronic 1, H410
according to Regulation (EC) No. 1272/2008 (CLP) and the Globally Harmonized System for Classification and Labeling of Chemicals (GHS).
According to Directive 67/548/EEC oleic-acid based IQAC, DMS quaternised has to be classified as hazardous to the environment as R50/53.
Acute toxicity values are below the value of≤ 1 mg/L and the substance is not readily biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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