Registration Dossier
Registration Dossier
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EC number: 612-179-8 | CAS number: 61597-98-6
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
The substance was found to be stable at pH 4, to hydrolyse very slowly at pH 7 and hydrolyse relatively rapidly at pH 9.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 771 d
- at the temperature of:
- 25 °C
Additional information
A valid hydrolysis study in accordance with OECD TG 111 was conducted. The results of a preliminary test indicated that further testing is required and the hydrolysis was studied in a main test at pH 7 and pH 9 with sample solutions being maintained at 50, 70 and 80 °C or 50, 60 and 70 °C. It was found that the substance was not hydrolysed at pH 4. Menthyl lactate showed very slow hydrolysis at pH 4 and relatively quick hydrolysis at pH 9. The reaction followed pseudo-first order kinetics. The half-life of hydrolysis at pH 4 was estimated to be > 1 year. The rate constants for the reaction at 25 °C were estimated by using the Arrhenius relationship and were 0.0000375 hr-1 at pH 7 and 0.00209 hr-1 at pH 9. This corresponds to half-lives of 771 days and 332 hours, respectively
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