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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 2012-03-08 to 2012-05-31
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- GLP study conducted in accordance with OECD and EU Guidelines with a valid GLP certificate.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- 1995
- Deviations:
- yes
- Remarks:
- The concentration of the oversaturated test item solution was 1 g/mL, however higher test item loading should have been applied according to the guideline. The 1 g/mL test item solution was very dense, and difficult to handle during filtration.
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- 2008
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Key result
- Water solubility:
- 704.34 g/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- 4.4
- Details on results:
- The water solubility of Reactive Yellow F01-0555 is given as the mean of the measured saturation concentration of Reactive Yellow F01-0555 dissolved in water following 24, 48, and 72 hours of equilibration, if these concentration values do not differ by more than 15%.
The mean of Reactive Yellow F01-0555 concentrations in the water samples obtained after 24h, 48h and 72h equilibration was 704.34 g/L. The coefficient of variation of the concentrations is 0.2% (see Table 3 below); therefore, the results meet with the accuracy criteria of the OECD Guideline 105. - Conclusions:
- Interpretation of results (migrated information): very soluble (> 10000 mg/L)
The mean of Reactive Yellow F01-0555 concentrations in the water samples obtained after 24h, 48h and 72h equilibration was 704.34 g/L. The coefficient of variation of the concentrations is 0.2% ; therefore, the results meet with the accuracy criteria of the OECD Guideline 105.
Water solubility of Reactive Yellow F01-0555 is 704.34 g/L at 20 ± 1°C. - Executive summary:
The purpose of this study was to determine the water solubility of Reactive Yellow F01-0555.which is specified by the saturation mass concentration of the test item in water at 20 ±1°C.
During the study, the flask method (OECD 105) was applied.
The water solubility of Reactive Yellow F01-0555 is given as the mean of the measured saturation concentration of Reactive Yellow F01-0555 dissolved in water following 24, 48, and 72 hours of equilibration, if these concentration values do not differ by more than 15%.
The mean of Reactive Yellow F01-0555 concentrations in the water samples obtained after 24h, 48h and 72h equilibration was 704.34 g/L. The coefficient of variation of the concentrations is 0.2% ; therefore, the results meet with the accuracy criteria of the OECD Guideline.
The water solubility of Reactive Yellow F01-0555 is 704.34 g/L at 20 ± 1°C.
Reference
Calibration with standard solutions
The following calibration samples were applied: 0.5, 1, 2, 5, 20 and 50 µg/mL. The calibration graph was calculated applying weighted linear regression using 1/concentration as weighting factor (Table 1).
Table 1. Regression data of analytical occasions
Analytical occasion |
Intercept |
Slope |
Correlation coefficient (r2) |
12 March 2012 |
325 |
11939 |
0.9999 |
13 March 2012 |
529 |
11533 |
0.9997 |
14 March 2012 |
541 |
11045 |
0.9999 |
The pH of water samples and Reactive Yellow F01-0555 concentration after 24 h , 48 h and 72 h equilibration are presented in Table 2 and Table 3, respectively.
Table 2. pH of Reactive Yellow F01-0555 solution after 24 h , 48 h and 72 h equilibration
Sample |
pH |
Sample |
pH |
Sample |
pH |
24h/1 |
4.40 |
48h/1 |
4.40 |
72h/1 |
4.40 |
24h/2 |
4.41 |
48h/2 |
4.40 |
72h/2 |
4.41 |
24h/3 |
4.41 |
48h/3 |
4.40 |
72h/3 |
4.41 |
Table 3. Reactive Yellow F01-0555 concentration of the water samples after 24 h, 48 h and 72 h equilibration.
Equilibration time |
Reactive Yellow F01-water (g/L) |
Mean (g/L) |
SD |
CV |
24h |
699.41 |
705.24 |
8.38 |
1.2% |
701.46 |
||||
714.85 |
||||
48h |
690.61 |
702.36 |
10.6 |
1.5% |
705.39 |
||||
711.08 |
||||
72h |
706.89 |
705.42 |
2.40 |
0.3% |
702.65 |
||||
706.73 |
||||
MEAN: (WATER SOLUBILITY) |
704.34 |
- |
- |
|
Confidence interval (95 %): |
17.69 |
- |
- |
|
CV: |
0.2% |
- |
- |
Description of key information
The water solubility of the substance is 704.34 g/L at 20 ± 1 °C.
Key value for chemical safety assessment
- Water solubility:
- 704.34 g/L
- at the temperature of:
- 20 °C
Additional information
The mean of Reactive Yellow F01-0555 concentrations in the water samples obtained after 24h, 48h and 72h equilibration was 704.34 g/L. The coefficient of variation of the concentrations is 0.2% ; therefore, the results meet with the accuracy criteria of the OECD Guideline 105. The water solubility of Reactive Yellow F01-0555 is 704.34 g/L at 20 ± 1°C.
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