Registration Dossier
Registration Dossier
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EC number: 928-729-8 | CAS number: 188416-20-8
Endpoint summary
Administrative data
Description of key information
An acute oral toxicity with rats (Lewis ect. , 1998) was available which is key study. This substance was demonstrated to be greater than 2000mg/kg bodyweight.
An acute dermal toxicity with rats (Lewis ect. , 1998) was available which is key study. This substance was demonstrated to be greater than 2000mg/kg bodyweight.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- discriminating dose
- Value:
- 2 000 mg/kg bw
- Quality of whole database:
- 1 (reliable without restriction)
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 2 000 mg/kg bw
- Quality of whole database:
- 1 (reliable without restriction)
Additional information
An acute oral toxicity with rats (Lewis ect., 1998) was conducted according to OECD 420. This substance was demonstrated to be greater than 2000mg/kg bodyweight.
An acute dermal toxicity with rats (Lewis ect., 1998) was conducted according to OECD 402. This substance was demonstrated to be greater than 2000mg/kg bodyweight.
Justification for selection of acute toxicity – oral endpoint
Study run to a method comparable with current guidelines and to GLP
Justification for selection of acute toxicity – dermal endpoint
Study run to a method comparable with current guidelines and to GLP
Justification for classification or non-classification
Oral LD50 >2,000 mg/kg (actual value >2,000 mg/kg)
Dermal LD50 >2,000 mg/kg (actual value >2,000 mg/kg)
Therefore in accordance with Regulation (EC) No. 1272/2008 Table 3.1.1 the substance is not classified for the acute toxicity endpoint.
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