Registration Dossier
Registration Dossier
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EC number: 202-761-6 | CAS number: 99-51-4
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Determination of ratio of concentrations of a compound in the two phases of a mixture of Octanol-Water at equilibrium
- GLP compliance:
- no
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- 4-nitro-o-xylene
- EC Number:
- 202-761-6
- EC Name:
- 4-nitro-o-xylene
- Cas Number:
- 99-51-4
- Molecular formula:
- C8H9NO2
- IUPAC Name:
- 4-nitro-o-xylene
- Test material form:
- other: Clear Liquid
- Details on test material:
- Substance Name : 4-nitro-o-xylene
Molecular Formula : C8H9NO2
Physical state : Liquid
Constituent 1
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- -0.154
- Temp.:
- 32 °C
- pH:
- 6.13
Applicant's summary and conclusion
- Conclusions:
- The n-octanol/water partition coefficient (Kow ; also known as log P) is defined as the ratio of the equilibrium concentrations of a dissolved substance in a 2-phase system consisting of the largely immiscible solvents n-octanol and water.
Octanol/water partition coefficient, Log pow, of 4-nitro-o-xylene is found to be -0.154. Based on the results, the substance is not likely to bioaccumulate in food chain. - Executive summary:
The n-octanol/water partition coefficient (Kow ; also known as log P) is defined as the ratio of the equilibrium concentrations of a dissolved substance in a 2-phase system consisting of the largely immiscible solvents n-octanol and water.
Octanol/water partition coefficient, Log pow, of 4-nitro-o-xylene is found to be -0.154. Based on the results, the substance is not likely to bioaccumulate in food chain.
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