Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1983
Report date:
1983

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
EU Method B.1 tris (Acute Oral Toxicity - Acute Toxic Class Method)
Deviations:
not specified
GLP compliance:
yes
Test type:
acute toxic class method

Test material

Constituent 1
Chemical structure
Reference substance name:
4-[[(2-aminophenyl)methyl]amino]cyclohexyl acetate
EC Number:
298-842-9
EC Name:
4-[[(2-aminophenyl)methyl]amino]cyclohexyl acetate
Cas Number:
93839-71-5
Molecular formula:
C13H20N2O.C2H4O2
IUPAC Name:
4-[[(2-aminophenyl)methyl]amino]cyclohexyl acetate

Test animals

Species:
rat
Strain:
other: Chbb: THOM
Sex:
male/female

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
other: bidestilliertes Wasser mit 0,1 % Zusatz Tween 80
Doses:
2000; 3160 and 5000 mg/kg
No. of animals per sex per dose:
5male and 5 female per dose
Control animals:
not specified

Results and discussion

Effect levelsopen allclose all
Sex:
male
Dose descriptor:
LD50
Effect level:
>= 3 160 - <= 5 000 mg/kg bw
Based on:
test mat.
Sex:
female
Dose descriptor:
LD50
Effect level:
>= 3 665.3 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion

Interpretation of results:
practically nontoxic
Remarks:
Migrated information Criteria used for interpretation of results: EU