Registration Dossier
Registration Dossier
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EC number: 700-886-5 | CAS number: 1378867-81-2
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Study period:
- 1974
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: (i) no information on housing and feeding conditions given, (ii) no pathology reporting, (iii) no information on test substance stability, batch and purity given
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 974
- Report date:
- 1974
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 401 (Acute Oral Toxicity)
- Deviations:
- no
- GLP compliance:
- no
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- 4-(4-methyl-3-pentenyl)cyclohex-3-ene-1-carbaldehyde
- EC Number:
- 253-617-4
- EC Name:
- 4-(4-methyl-3-pentenyl)cyclohex-3-ene-1-carbaldehyde
- Cas Number:
- 37677-14-8
- Molecular formula:
- C13H20O
- IUPAC Name:
- 4-(4-methylpent-3-en-1-yl)cyclohex-3-ene-1-carbaldehyde
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- no data
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- other:
- Doses:
- 5000 mg/kg bw.
- No. of animals per sex per dose:
- 10 animals
- Control animals:
- not specified
- Details on study design:
- - Duration of observation period following administration: 14 days
- Frequency of observations: daily
- Necropsy of survivors performed: no
- Other examinations performed: clinical signs - Statistics:
- not needed
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 5 000 mg/kg bw
- Based on:
- test mat.
- Mortality:
- 0
- Clinical signs:
- other: slightly lethargy
- Gross pathology:
- no data
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- LD50 > 5000 mg/kg bw
According to Directive 67/548/EEC and its subsequent amendments, 4-(4-Methyl-pent-3-enyl)-cyclohex-3-enecarbaldehyde should not be classified as acute oral toxic.
According to the Regulation (EC) No 1272/2008 and subsequent regulations, 4-(4-Methyl-pent-3-enyl)-cyclohex-3-enecarbaldehyde should not be classified as acute oral toxic.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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