Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
(Q)SAR
Adequacy of study:
key study
Study period:
2010
Reliability:
3 (not reliable)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
In silico prediction
GLP compliance:
no
Test type:
other: in silico prediction

Test material

Constituent 1
Chemical structure
Reference substance name:
1,2,4-triazolo[4,3-a]pyridin-3(2H)-one
EC Number:
230-191-8
EC Name:
1,2,4-triazolo[4,3-a]pyridin-3(2H)-one
Cas Number:
6969-71-7
Molecular formula:
C6H5N3O
IUPAC Name:
[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

Test animals

Species:
other: mouse and rat

Results and discussion

Effect levels
Remarks on result:
other: Acute toxicity overview indicates for the most part of LD50 value low reliability index.

Applicant's summary and conclusion

Interpretation of results:
other: not reliable
Conclusions:
Acute toxicity overview indicates for the most part of LD50 value low reliability index.