Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 217-617-8 | CAS number: 1912-24-9
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 14 June 1993 to 27 May 1994
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Report date:
- 1994
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)
- Deviations:
- not specified
- GLP compliance:
- yes
Test material
- Reference substance name:
- Atrazine
- EC Number:
- 217-617-8
- EC Name:
- Atrazine
- Cas Number:
- 1912-24-9
- Molecular formula:
- C8H14ClN5
- IUPAC Name:
- 6-chloro-N2-ethyl-N4-(propan-2-yl)-1,3,5-triazine-2,4-diamine
- Details on test material:
- Batch n. C103330. CH20512
Purity: 99.9%
Expiry May 1996
Appaerance: white powder
Storage conditions: room temperature
Constituent 1
- Radiolabelling:
- no
Study design
- Analytical monitoring:
- yes
- Estimation method (if used):
- HPLC
Duration of test
- Duration:
- 5 h
- pH:
- 5
- Initial conc. measured:
- 1 500 µg/L
Results and discussion
- Transformation products:
- yes
Identity of transformation products
- No.:
- #1
Reference
- Reference substance name:
- Unnamed
- IUPAC name:
- atrazine 2 hydroxy
- Identifier:
- common name
- Identity:
- atrazine 2 hydroxy
Total recovery of test substance (in %)open allclose all
- % Recovery:
- 57.25
- pH:
- 5
- Temp.:
- 50 °C
- Duration:
- 5 h
- % Recovery:
- 64.55
- pH:
- 5
- Temp.:
- 60 °C
- Duration:
- 5 h
- % Recovery:
- 45.28
- pH:
- 5
- Temp.:
- 70 °C
- Duration:
- 5 h
Dissipation DT50 of parent compoundopen allclose all
- pH:
- 5
- Temp.:
- 60 °C
- Hydrolysis rate constant:
- 0.11 d-1
- DT50:
- 6.6 d
- Type:
- (pseudo-)first order (= half-life)
- pH:
- 5
- Temp.:
- 70 °C
- Hydrolysis rate constant:
- 0.19 d-1
- DT50:
- 3.7 d
- Type:
- (pseudo-)first order (= half-life)
- pH:
- 5
- Temp.:
- 25 °C
- Hydrolysis rate constant:
- 0.01 d-1
- DT50:
- 69.6 d
- Type:
- (pseudo-)first order (= half-life)
- Remarks on result:
- other: rate costant and half time for 25°C are derived from the 60 and 70°C values.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Remarks:
- No peaks at the characteristic retention volume of the test substance were obtained in the chromatograms of the blank solutions, indicating that the analytical procedure was free from interferences.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
