Registration Dossier
Registration Dossier
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EC number: 203-977-3 | CAS number: 112-49-2
Endpoint summary
Administrative data
Description of key information
A 29 day oral toxicity study was performed in rats. The animals were exposed to 0, 62.5, 250 and 1000 mg/kg bw/d. At 1000 mg/kg/d, males exhibited decreased testes and epididymides that correlated with microscopical indications of impaired spermatogenesis.
Key value for chemical safety assessment
Repeated dose toxicity: via oral route - systemic effects
Endpoint conclusion
- Dose descriptor:
- NOAEL
- 250 mg/kg bw/day
- Study duration:
- subacute
- Species:
- rat
Additional information
Justification for classification or non-classification
The repeated dose toxicity of Triethylene glycol dimethyl ether was investigated according to OECD 407. NOAEL of 250 mg/kg/d was obtained. No classification with respect to the endpoint repeated dose toxicity is justified.
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