Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 939-270-8 | CAS number: -
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
The UVCB substance to be registered is a mixture of the two Guerbet alcohols 2 -hexyldecan-1-ol & 2-octyldodecan-1 -ol and their corresponding esters with C12 and C14 fatty acids. Genetic toxicity studies are available for the two Guerbet alcohols and for the UVCB substance as such.
Experimental data on in vitro mutagenicity on bacteria are furthermore available nearly all representatives of the category of Guerbet alcohols, as evaluated by the REACH consortium in charge of this substance group. All tests are negative. Studies on mammalian cells are only available for the C16 Guerbet alcohol (2 -hexyldecan-1-ol , CAS-No. 2425-77-6). Both a cytogenetic assay (chromosome aberration test) and a gene mutation study (HPRT test) are negative. Due to the similar structure with no additional functional groups, these data can be cross-read to 2-octyldodecan-1 -ol , the second Guerbet alcohol present in the UVCB.
A gene mutation study (HPRT test) was conducted with the UVCB substance to be registered to support the data set for genetic toxicity. In the HPRT test, the UVCB did not induce mutations.
Altogether, no indication exists for a mutagenic potential of the UVCB substance to be registered.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
Avalaible data are conclusive but not sufficient for classification of 2-hexyldecan-1-ol with regard to mutagenicity / genotoxicity.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
