Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 810-161-6 | CAS number: 1229654-66-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
If the substance is released to the environment it will be
transported and distributed depending on its substance specific
properties (e.g. physico-chemical properties, log Koc).
Based on the vapour pressure of 3.2 x 10E-6 Pa at 20 °C it can be
concluded that volatilization of the substance in the environment is not
expected. Thus, the substance is expected to partition mainly to the
water phase (water solubility: approx. 1 mg/L) with potential for
adsorption to sediment particles based on its log Koc of 2.33. In soil
the mobility for adsorption and desorption is considered to be low.
In the environment the substance will undergo several abiotic and biotic
transformation/degradation processes. Hydrolysis as well as
photodegradation and biotic degradation contribute to the overall
environmental fate of the substance. Bioaccumulation in biota and
biomagnification within the food chain is not expected. An experimental
BCF of < 2 indicated that the substance has a low potential for
bioaccumulation.
For hydrolysis the experimental data could be well described by a single
first order (SFO) kinetic model. The hydrolytic degradation of the
substance was observed to be pH dependent. At 20 °C the experimental
half-lives were 265, 58.0 and 1.27 d for pH 4, 7 and 9, respectively.
One major metabolite was found during the process of hydrolysis.
Therefore, hydrolysis is an important route of dissipation for the
substance in water.
Photolytic degradation in sterile buffer and in natural water was
studied. From experimental results, in sterile buffer the predicted
environmental DT50 values are calculated to be e.g. 10.5 solar summer
days at Phoenix, Arizona, USA. The calculated DT50 value for the
substance under dark conditions was 188.5 d. Degradation of the
substance in irradiated samples was accompanied by the formation of one
major degradation product.
The photolytic route and rate of degradation of the substance was also
measured in sterile natural water (pH 8.0 to 8.5) with 14C-marked test
item at 25 °C. Up to four degradation products and carbon dioxide (max.
formation 38.9%AR) were identified in irradiated samples. The half-life
of the substance in irradiated samples was 0.7 d and 0.77 d. The
predicted environmental DT50 values were calculated to be e.g. 4.7 and
4.9 solar summer days at Tokyo, Japan. Under dark conditions the
substance degraded to one major metabolite and had an experimental DT50
value of between 0.3 and 0.75 d. Formation of carbon dioxide in dark
samples was insignificant at ≤ 0.1%AR. Therefore, photodegradation was
found to contribute to the overall degradation of the substance under
aqueous conditions in natural water.
In a biodegradation screening study according to OECD 301 F the
substance was found to be not readily biodegradable under the test
conditions at the end of the 28-day exposure period. Simulation studies
investigating the degradation in aerobic and anaerobic water sediment
systems were conducted in order to assess further the degradation in the
environment.
Aerobic aquatic metabolism of the substance was studied in two
water sediment systems with 14C-marked test substance. Carbon dioxide
was formed at a maximum of 0.2%AR at study end (DAT-101), and
non-extractable residues were formed at a maximum of 12.1%AR at DAT-29.
Two degradation products were identified at a maximum of 84.8%AR at
DAT-59 and 9.2%AR at DAT-101. The rate of degradation ranged from a DT50
of 5.3 to 6.3 d in water to a DT50 of 11.1 to 122 d in the entire
system.
Anaerobic aquatic metabolism of the substance was studied in two water
sediment systems with 14C-marked test substance. Carbon dioxide and
volatile organic compounds were formed at a maximum of 0.4%AR at DAT-12,
and non-extractable residues were formed at a maximum of 10.4%AR at
DAT-82. One degradation products was identified, at a maximum of 40.4%AR
at DAT-104. The rate of degradation ranged from a DT50 of 16.0 to 24.1 d
in water to a DT50 of 103.5 to 217.9 d in the entire system.
In both aerobic and anaerobic metabolism studies, degradation rates were
higher in systems where the pH was more alkaline, illustrating the
importance of abiotic hydrolysis in the degradation pathway. In
conclusion the substance is not considered to be rapidly degraded in the
environment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.