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Diss Factsheets
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EC number: 206-076-3 | CAS number: 299-29-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: screening test, other
- Remarks:
- Biodegradability in Seawater
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 10 October 2000 to 7 November 2000
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Remarks:
- Followed OECD Guideline 306 but missing some information in report
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 306 (Closed Bottle Procedure)
- GLP compliance:
- yes
- Remarks:
- Followed UK GLP Regulations 1997
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- natural water
- Details on inoculum:
- All test bottles contained coarse filtered, natural seawater as inoculum. For each of the sample days, duplicate bottles were prepared for each of the test material concentrations and reference material. Three repIicates for the control vessels were prepared. During the study, all bottles were incubated at 17.0-19 .5°C, in the dark.
Natural seawater was collected from Penrhyn Point in North Wales on 27th September 2000. The temperature at collection was 16.7°C, pH 8.13, salinity 28.5 g/L and the dissolved oxygen level 91.6%. After collection the seawater was coarse filtered and maintained in the dark. The seawater was aged prior to use by gentle aeration, at 20± 2°C. - Duration of test (contact time):
- 28 d
- Initial conc.:
- 6 mg/L
- Initial conc.:
- 7.5 mg/L
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Test Vessel: Completely filled, sealed glass BOD bottles of nominal 272 ml volume.
Dissolved oxygen (DO) concentrations were measured on sample days 0, 3, 7, 14, 21 and 28. Duplicate bottles of each concentration of test material, and bottles containing the reference compound (sodium benzoate) were measured. On each occasion three blank bottles were also measured. - Reference substance:
- other: Sodium benzoate
- Parameter:
- % degradation (O2 consumption)
- Value:
- ca. 79.3
- Sampling time:
- 28 d
- Remarks on result:
- other: Concentration 6.0 mg/L
- Parameter:
- % degradation (O2 consumption)
- Value:
- ca. 78.4
- Sampling time:
- 28 d
- Remarks on result:
- other: Concentration 7.5 mg/L
- Details on results:
- The results at both 6.0 mg/L and 7.5 mg /L indicated that under these conditions, the test substance showed good potential for degradation. At 28 days the calculated percentage degradation values were 79.3% at a concentration of 6.0 mg/L and 78.4% at 7.5 mg/L.
- Parameter:
- COD
- Value:
- 0.66 mg O2/g test mat.
- Interpretation of results:
- readily biodegradable, but failing 10-day window
- Conclusions:
- Readily biodegradable based on 28 day oxygen consumption of 79.3% and 78.4%.
- Executive summary:
In this study, the test substance was assessed for the rate and extent of biodegradation when exposed to marine microorganisms for 28 days according to the method detailed in STL Runcorn SOP III.36 and in accordance with OECD guideline 306.
The results indicated that, under the test conditions detailed, the test material showed good potential for degradation in the marine environment at the concentrations tested. At 28 days the calculated percentage degradation values were 79.3% at a concentration of 6.0 mg/L and 78.4% at 7.5 mg/L.
Reference
Biochemical Oxygen Demand of Test Substance
02 Depletion ( mg BOD/L) | Day 3 | Day 7 | Day 14 | Day 21 | Day 28 |
Test material 6.0 mg/L BODx= (mao- max ) - (mdo- mdx) |
1.62 | 2.48 | 2.65 | 3.05 | 3.14 |
Test material 7.5 mg/L BODx= (mb0- mbx)- (mdo- mdx) |
1.71 | 2.72 | 2.92 | 3.32 | 3.88 |
Reference- 2.50 mg/L sodium benzoate BODx= (mco- mcx) - (mdo- mdx) |
2.68 | 3.09 | 3.21 | 3.28 | 2.81 |
Description of key information
Readily biodegradable based on 28 day oxygen consumption of 79.3% and 78.4%.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable but failing 10-day window
Additional information
In this study, the test substance was assessed for the rate and extent of biodegradation when exposed to marine microorganisms for 28 days according to the method detailed in STL Runcorn SOP III.36 and in accordance with OECD guideline 306.
The results indicated that, under the test conditions detailed, the test material showed good potential for degradation in the marine environment at the concentrations tested. At 28 days the calculated percentage degradation values were 79.3% at a concentration of 6.0 mg/L and 78.4% at 7.5 mg/L.
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