Registration Dossier
Registration Dossier
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EC number: 431-060-1 | CAS number: 153719-38-1
Endpoint summary
Administrative data
Description of key information
Substance was tested for dermal irritation in rabbits (OECD 404). Irritation was checked at 1, 24, 48, and 72 hours. No erythema or edema > score 1 was observed. All erythema was fully reversible. Mean erythema score was 0.67. Mean edema score was 0.11.
Substance was tested for eye irritation in the rabbit (OECD 405). Effects were observed in all four criteria, but scores were low. All effects were fully reversible, with no remaining effects on day seven in all animals. Mean score for Cornea was 0.22, for Iris 0.83, for Conjunctivae 1, and for Chemosis 0.44.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
Substance is not irritating to skin, and slightly irritating to eyes.
Effects on eye irritation: slightly irritating
Justification for classification or non-classification
Effects observed in dermal and eye irritation tests do not exceed trigger values for classification.
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