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EC number: 424-310-4 | CAS number: 178452-66-9 BLUE PE 3811
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From July 9th to 11th, 1996
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.2 (Acute Toxicity for Daphnia)
- Version / remarks:
- December 29th, 1992
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Version / remarks:
- Aprile 4th, 1984
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- yes
- Vehicle:
- no
- Details on test solutions:
- The nominal concentrations tested were 9, 19, 41, 91 and 200 mg /l test substance. Additionally, a control group (test water without addition of the test substance) was tested in parallel. The analytically determined test substance concentrations in the analysed test medium of 200 mg/l varied in the range from 95 % to 105 % of the nominal value. In the test medium the test substance was sufficiently stable during the test period of 48 hours. Therefore, all reported biological results are related to the nominal concentration of the test substance.
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- 20 daphnids tested per control
20 daphnids tested per each test concentration - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
- Hardness:
- 250 mg CaCO3/l
- Test temperature:
- The test media temperatures ranged from 20.4 to 20.8 °C.
- pH:
- The measured pH-values in the test media ranged from pH 7.1 to pH 7.9.
- Dissolved oxygen:
- >= 8.3 mg/l
- Nominal and measured concentrations:
- Nominal concentrations of the test substance = 9, 19, 41, 91, 200 mg/l.
The analytically determined test substance concentrations in the analysed test medium of 200 mg/l varied in the range from 95 % to 105 % of the nominal value. In the test medium the test substance was sufficiently stable during the test period of 48 hours. Therefore, all reported biological results are related to the nominal concentration of the test substance. - Details on test conditions:
- In Milli-Q-water salts were added: CaCl2 × 2H2O (2.0 mmo/L = 294.0 mg/l), MgSO4 × 7H2O (0.5 mmol/L = 123.0 mg/l), NaHCO3 (0.75 mmol/l = 65.0 mg/l), KCI (0.75 mmol/l = 5.8 mg/l). Water was aerated to oxygen saturation.
- Reference substance (positive control):
- no
- Duration:
- 48 h
- Dose descriptor:
- EC0
- Effect conc.:
- > 200 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 200 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 200 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC100
- Effect conc.:
- > 200 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 200 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- LOEC
- Effect conc.:
- > 200 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- In the control and up to and including the test concentration of 200 mg/l of the test substance no significant rate of immobility or mortality of the test animals was observed during the test period of 48 hours. The immobilization rate of 10 % in the control does not have any influence on the validity of the test because according to the test guidelines this immobilization rate is tolerated in the control and additionally, no other signs of intoxication were observed. In all the test concentrations the test animals were coloured by the test substance. However, this colouration of the Daphnids had no detrimental impact on the survival rate or mobility of the test animals. Therefore, the 48-hour NOEC and the 48-hour EC 0 of Blue PE 3811 to Daphnia magna were determined to be at least 200 mg/l of the test substance. The NOEC might even be higher than this concentration. The 48-hour LOEC, the 48-hour EC 50 and the 48-hour EC 100 were clearly higher than this test concentration. These values could not be quantified, since concentrations in excess of nominal 200 mg/l of the test substance have not been tested. All test media were coloured by the test substance. After 48 hour test duration a small part of the test substance had settled on the bottom ofthe glass beaker and an adsorption of the test substance onto the walls of the test beakers was observed.
- Conclusions:
- The test substance has no toxic effects on the daphnids up to 200 mg/l concentration.
- Executive summary:
The short-term acute toxicity to aquatic invertebrates was determined according to OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test).
NOEC (48 h) = 200 mg/L
LOEC (48 h) > 200 mg/L
EC50 (48h) >200 mg/L
Reference
Description of key information
The test substance hasn't toxic effects on daphnids up to 200 mg/l concentration.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- EC50
- Effect concentration:
- > 200 mg/L
Additional information
The short-term acute toxicity to aquatic invertebrates was determined according to OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test).
NOEC (48 h) = 200 mg/L
LOEC (48 h) > 200 mg/L
EC50 (48h) >200 mg/L
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