Cuprate(3-), [3-[2-[5-(hydroxy-.kappa.O)-4-[2-[1-(hydroxy-.kappa.O)-6-(phenylamino)-3-sulfo-2-naphthalenyl]diazenyl-.kappa.N1]-2-methylphenyl]diazenyl]-1,5-naphthalenedisulfonato(5-)]-, sodium (1:3)

Short-term toxicity to fish

Administrative data

Endpoint:

short-term toxicity to fish

Type of information:

experimental study

Adequacy of study:

key study

Study period:

1985

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Analogue substance tested.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1985

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

EU Method C.1 (Acute Toxicity for Fish)

GLP compliance:

yes

Test material

Test material information

Constituent 1

Reference substance name:

Analogue substance (refer to IUCLID chapter 13)

IUPAC Name:

Analogue substance (refer to IUCLID chapter 13)

Test organisms

Test organisms (species):

Cyprinus carpio

Study design

Test type:

static

Water media type:

freshwater

Total exposure duration:

96 h

Results and discussion

Effect concentrations

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

46 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Applicant's summary and conclusion

Conclusions:

The test was conducted with the analogue substance. Based on the 96-hour acute toxicity study of the analogue substance in carp the LC50 was determined to be 46 mg/L. Due to structural similarity of the substance subject of registration including comparable bioavailability it can be concluded that the LC50 for the substance subject of registration will be in a comparable range, i.e. in the range of 10 - 100 mg/L.