Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 252-156-6 | CAS number: 34690-00-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
No study of toxicity to micro-organisms is available for BHMT-H. A reliable study, performed with a Na/H salt of EDTMP, is available. The EC50 to WWTP micro-organisms was determined to be >100 mg/L as active acid. In view of the low level of inhibition seen at a loading of 100 mg/l, it is acceptable to interpret this value as an EC5. This result comes from a reliable study conducted according to an appropriate test protocol, and in compliance with GLP.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 100 mg/L
Additional information
5.4% inhibition was seen at 100 mg/L loading (in terms of active acid), thus the EC50 is >100 mg/l. No NOEC or EC5 was derived by the report authors, however in view of the low level of inhibition (approximately 5%) seen at a loading of 100 mg/l, it is considered acceptable to interpret this concentration as an approximation of the EC5 for the purpose of PNEC derivation.
There is no data available for the toxicity of BHMT to aquatic microorganisms, therefore data have been read-across from structural analogue, EDTMP.
BHMT acid (CAS 34690-00-1) has three amine centres (five methylphosphonate groups), connected by hexyl chains. EDTMP acid (CAS 1429-50-1) has two aminobismethylphosphonate groups, connected by an ethyl chain.
As well as being structural analogues, both phosphonates have consistent chemical properties including high MW (685 and 436 respectively), very low log Kow(≤-4 for both substances) and are highly soluble in water. The substances generally posses similar physico-chemical properties and are not readily biodegradable.
The sodium counterion of EDTMP-xNa (22036-77-7) is not significant in respect of the properties under consideration and has been assessed in depth in the public literature.Additionally, the counterion is expected to dissociate when in contact with water, including atmospheric moisture.
Therefore, for the purpose of this assessment, read-across is considered valid.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.