Registration Dossier
Registration Dossier
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EC number: 233-593-1 | CAS number: 10254-57-6
Endpoint summary
Administrative data
Description of key information
Additional information
Rainbow trout (Oncorhynchus mykiss) were exposed to commercial diet treated with radiolabeled test material at a nominal concentration of 1000 µg/g over a 14-day exposure period followed by a depuration period of 28 days, under continous flow-through conditions at 14 deg C. No mortalities or sub lethal effects of exposure were observed through the test.
Radioactivity was accumulated in fish tissues following exposure to feed treated with the test material for 14 days. The kinetic dietary biomagnification factor (BMFk) was determined to be 0.129. The fish lipid normalized biomagnification factor corrected for growth rate (BMFkgL) was determined to be between 0.777 (based on 15% lipid food content) and 1.04 (based on 20% lipid food content). The growth corrected half-life (t1/2) was determined to be 24.1 days.
At Day 28 of the depuration phase, eliminated radioactivity accounted for approximately two half lives of that which had been accumulated.
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