Registration Dossier
Registration Dossier
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EC number: 272-574-2 | CAS number: 68890-66-4
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Justification for type of information:
- Data is from safety assesment report
- Qualifier:
- according to guideline
- Guideline:
- other: refer principle below
- Principles of method if other than guideline:
- The half life of hydrolysis of test chemical was determined in acidic and basic conditions.
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Name of test material: Piroctone olamine
- Molecular formula: C14H23NO2C2H7NO
- Molecular weight: 298.424 g/mol
- Substance type: Organic
- Physical state: solid - Radiolabelling:
- not specified
- Analytical monitoring:
- not specified
- Positive controls:
- not specified
- Negative controls:
- not specified
- Transformation products:
- yes
- No.:
- #1
- Key result
- DT50:
- > 1 - <= 10 d
- Type:
- not specified
- Remarks on result:
- other: slowly hydrolysable
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The half life of hydrolysis of test chemical was estimated to be in range 1- 10 days. Therefore it is concluded that test chemical is slowly hydrolysable.
- Executive summary:
The half life of hydrolysis of test chemical was estimated to be in range 1- 10 days and transformaton product identified was (2E,4Z)-5 -(hydroxyamino)-3,7,9,9 -tetramethyl-deca-2,4 -dienoic acid . Therefore it is concluded that test chemical is slowly hydrolysable.
Reference
Description of key information
The half life of hydrolysis of test chemical was estimated to be in range 1- 10 days and transformaton product identified was (2E,4Z)-5 -(hydroxyamino)-3,7,9,9 -tetramethyl-deca-2,4 -dienoic acid . Therefore it is concluded that test chemical is slowly hydrolysable.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 5 d
- at the temperature of:
- 25 °C
Additional information
The half life of hydrolysis of test chemical was estimated to be in range 1- 10 days and transformaton product identified was (2E,4Z)-5 -(hydroxyamino)-3,7,9,9 -tetramethyl-deca-2,4 -dienoic acid . Therefore it is concluded that test chemical is slowly hydrolysable.
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