Registration Dossier
Registration Dossier
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EC number: 439-840-1 | CAS number: 20846-91-7
Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
Description of key information
In a GLP study conducted according to OECD Guideline 106, the solubility of trisodium EDDS in a standard fat was up to 4 mg/kg at 37oC (de Vries, 1993c)
Key value for chemical safety assessment
Additional information
In a GLP study conducted according to OECD Guideline 106, the solubility of trisodium EDDS in a standard synthetic fat (HB307) was determined by stirring the test material (100 or 400 mg) with the fat solvent (50 or 25 mL respectively) at 37oC for up to 48 h. The concentration of the test material in the fat phase was measured by HPLC.
The analysed concentrations of trisodium EDDS varied from 0.09 to 3.57 mg/kg. Due to the significant variation between measurements, the fat solubility was taken to be equal to or less than 3.57 mg/kg (the highest concentration analysed) (de Vries, 1993c).
[Data on trisodium EDDS is considered relevant to use for understanding the potential fat solubility of EDDS acid, and is acceptable for using as read-across information].
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