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Diss Factsheets
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EC number: 469-500-8 | CAS number: 857035-95-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 19 October to 17 November 2006
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: compliant to GLP and testing guideline; adequate coherence between data, comments and conclusions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 007
- Report date:
- 2007
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-C (Determination of the "Ready" Biodegradability - Carbon Dioxide Evolution Test)
- Deviations:
- no
- GLP compliance:
- yes
Test material
Reference
- Name:
- Unnamed
- Type:
- Constituent
- Details on test material:
- - Name of test material (as cited in study report): R0054002C, synonym IMEXINE OBH
- Physical state: beige to yellow powder
- Purity: 99.7%
- Impurities (identity and concentrations): not indicated
- Purity test date: 20 July 2006
- Lot/batch No.: R0054002C 013 L 001, synonym 0604070001
- Expiration date of the lot/batch: 01 August 2007
- Stability under test conditions: not indicated
- Storage condition of test material: at room temperature and under nitrogen gas
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of activated sludge: water treatment plant of Evreux (France)
- Laboratory culture: CIT
- Preparation at receipt : by initially decanting and sieving the sludge to concentrate the suspended matter and remove the biggest particles. The sludge was centrifuged for 5 minutes, the supernatant was rejected and the pellet redipersed in the mineral medium.
- Storage conditions: T 22 +/- 2°C, air bubbled through the inoculum until use
- Storage length: 6 days
- Preparation of inoculum for exposure: centrifugation and redispersion of pellet in the mineral medium
- Preatreatment: no
- Concentration of sludge: 3.7 g/L
- Water filtered: no - Duration of test (contact time):
- ca. 28 d
Initial test substance concentration
- Initial conc.:
- 10 mg/L
- Based on:
- other: Total Organic Content
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of medium: deionized water which contained no more than 5% of the organic carbon content
- Test temperature: 19 to 24°C
- pH: 7.27 to 7.82
- pH adjusted: no
- Continuous darkness: yes
TEST SYSTEM
- Number of culture flasks/concentration: 2
- Method used to create aerobic conditions: the test flasks were constantly aerated with CO2-scrubbed air and constantly agitated by magnetic stirring.
- Measuring equipment: titration method with 0.05 M HCl, using phenolphtalein as an indicator.
CONTROL AND BLANK SYSTEM
- Inoculum blank: two flasks
- Reference control: one flask (sodium acetate at 10.0 mg/L of TOC)
- Toxicity control: one flask (test item at 10.0 mg/L of TOC and sodium acetate at 10.0 mg/L of TOC and inoculum)
Reference substance
- Reference substance:
- acetic acid, sodium salt
Results and discussion
- Test performance:
- All validity criteria were respected:
- the blank value was < 70 mg of CO2/L at the end of the test (43.3 mg/L)
- biodegradation in the reference test was at least 60 % after 14 days
- biodegradation in the toxicity control was at least 25% after 14 days
- biodegradation values of test item replicates deviated by less than 20% at the end of the 10-day window and at the end of the 28-day period of the test
% Degradationopen allclose all
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 28
- Sampling time:
- 17 d
- Remarks on result:
- other: End of the 10-day window
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 27
- Sampling time:
- 28 d
- Details on results:
- No significant inhibition of the inoculum activity due to toxicity of the test item was noted in this test.
BOD5 / COD results
- Results with reference substance:
- The reference item degraded normally under the test conditions.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: Not readily biodegradable
- Conclusions:
- The biodegradation of the test item reached 28% at the end of the 10-day window on the 17th day and 27% at the end of the test. The test item was therefore not readily biodegradable in the 28-day modified Sturm test.
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