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EC number: 212-104-5 | CAS number: 762-72-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 15 Feb - 19 Mar 2019
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 019
- Report date:
- 2019
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Version / remarks:
- 1992
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-D (Determination of the "Ready" Biodegradability - Manometric Respirometry Test)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 835.3110 (Ready Biodegradability)
- Version / remarks:
- Paragraph (q)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- The Department of Health of the Government of the United Kingdom
Test material
- Reference substance name:
- Allyltrimethylsilane
- EC Number:
- 212-104-5
- EC Name:
- Allyltrimethylsilane
- Cas Number:
- 762-72-1
- Molecular formula:
- C6H14Si
- IUPAC Name:
- trimethyl(prop-2-en-1-yl)silane
- Test material form:
- liquid
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum: A mixed population of sewage treatmentmicro-organisms was obtained on 18 February 2019 from the final effluent stage of the Severn Trent Water Plc sewage treatment plant at Loughborough, UK, which treats predominantly domestic sewage.
- Preparation of inoculum for exposure: The sample of effluent was filtered through coarse filter paper (first approximate 200 mL discarded) and maintained on aeration in a temperature controlled room at approximately 20 °C prior to use. The deionized reverse osmosis water used for the preparation of the mineral medium and the mineral medium used for the test contained less than 1 mg/L Total Organic Carbon.
- Initial inoculum rate in vessel: Inoculum rate of 1% v/v
- Water filtered: yes - Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Details on study design:
- TEST CONDITIONS
- Composition of medium: mineral medium (composition recommended by OECD guideline 301)
- Test item preparation: Due to the volatile nature of the test item, the test item was added directly to the test vessels. An aliquot of mineral medium (495 mL) was dispensed into each test vessel. An aliquot of inoculum (5 mL) was added prior to an amount of test item (70 µL, equivalent to 50 mg of test item determined by preliminary weighings) being dispensed into the inoculated mineral medium to give the test concentration of 100 mg/L.
- Test temperature: 19 - 21°C
- pH: 6.0 - 8.5
- pH adjusted: no
- Aeration of dilution water: yes
- Continuous darkness: no, diffuse light
TEST SYSTEM
- Culturing apparatus: 500 mL bottles
- Number of culture flasks: 3 replicates (mineral medium and the test item at a concentration of 100 mg/L)
- Method used to create aerobic conditions: Prior to the start of the test, the purified water was aerated for approximately 20 hours at the test temperature to give a dissolved oxygen concentration of approximately 9 mg O2/L.
- Measuring equipment: Hach HQ40d Flexi handheld meter (pH measurement), CES Multi-Channel Aerobic Respirometer
- Test performed in closed vessels due to significant volatility of test substance: yes
- Test performed in open system: no
- Details of trap for CO2: flask were sealed by a sensor head/CO2 trap.
- Conditions: The samples were stirred for the duration of the test with a magnetically coupled stirrer. Flaks were immersed in a temperature controlled water bath.
SAMPLING
- Sampling frequency: Biological Oxygen Demand: daily (inoculum control, test item, procedure control and the toxicity control), temperature: daily (water bath), pH: day 0 (in all test vessels before addition of the inoculum and then if applicable the test item), day 28 (two inoculum controls, one procedure control, two test item and one toxicity control vessel)
CONTROL AND BLANK SYSTEM
- Inoculum blank: 3 replicates (inoculated mineral medium to act as the inoculum control)
- Procedure control: 2 replicates (inoculated mineral medium and the reference item, aniline, at a concentration of 100 mg/L)
- Toxicity control: 2 replicates (the test item at a concentration of 100 mg/L in inoculated mineral medium plus reference item, aniline, at a concentration of 100 mg/L
Reference substance
- Reference substance:
- aniline
- Remarks:
- 100 m/L
Results and discussion
% Degradation
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 10
- Sampling time:
- 28 d
BOD5 / COD results
- Results with reference substance:
- Aniline (procedure control) attained 69% biodegradation after 14 days in a 10-Day Window and 73% biodegradation after 28 days thereby confirming the suitability of the inoculum and test conditions.
Any other information on results incl. tables
Table 1: Biological Oxygen Demand (BOD) Values.
Day |
BOD (mg O2/L) |
|||||
Inoculum Control |
Procedure Control |
Test Item |
Toxicity Control |
|||
R1 |
R2 |
R1 |
R2 |
|||
0 |
0.00 |
0.00 |
0.00 |
0.00 |
0.00 |
0.00 |
1 |
0.24 |
0.16 |
0.24 |
6.12 |
6.24 |
6.16 |
2 |
0.66 |
0.50 |
0.92 |
11.00 |
10.66 |
10.46 |
3 |
0.66 |
0.96 |
2.74 |
15.08 |
13.86 |
14.42 |
4 |
1.00 |
1.80 |
12.38 |
18.08 |
16.42 |
22.44 |
5 |
1.24 |
2.58 |
67.44 |
20.20 |
18.32 |
80.00 |
6 |
2.16 |
3.70 |
138.24 |
22.50 |
20.46 |
150.48 |
7 |
2.88 |
4.54 |
176.30 |
24.16 |
22.00 |
182.56 |
8 |
3.38 |
5.28 |
187.84 |
25.62 |
23.36 |
188.68 |
9 |
3.84 |
5.96 |
196.54 |
26.78 |
24.54 |
192.22 |
10 |
4.24 |
6.16 |
204.96 |
27.40 |
25.08 |
195.22 |
11 |
4.70 |
7.08 |
210.46 |
28.70 |
26.36 |
199.42 |
12 |
5.42 |
7.96 |
213.92 |
29.86 |
27.70 |
203.92 |
13 |
6.46 |
9.08 |
217.42 |
31.32 |
29.20 |
208.08 |
14 |
7.28 |
10.00 |
220.66 |
32.44 |
30.36 |
211.08 |
15 |
8.08 |
10.66 |
223.86 |
33.16 |
31.12 |
213.16 |
16 |
8.46 |
11.32 |
227.82 |
34.36 |
32.32 |
215.92 |
17 |
9.08 |
12.04 |
230.40 |
35.40 |
33.40 |
218.00 |
18 |
9.74 |
12.70 |
232.20 |
36.28 |
34.28 |
219.92 |
19 |
10.16 |
13.46 |
234.04 |
37.52 |
35.48 |
222.20 |
20 |
10.78 |
14.16 |
235.40 |
38.56 |
36.44 |
224.66 |
21 |
11.38 |
14.66 |
236.16 |
39.06 |
36.98 |
228.32 |
22 |
11.92 |
15.28 |
237.12 |
39.82 |
37.70 |
234.12 |
23 |
11.92 |
15.28 |
237.86 |
40.16 |
38.02 |
240.28 |
24 |
11.92 |
15.78 |
238.98 |
41.10 |
39.02 |
244.70 |
25 |
12.90 |
16.32 |
239.94 |
41.94 |
39.86 |
248.48 |
26 |
14.20 |
16.82 |
240.82 |
42.74 |
40.60 |
252.20 |
27 |
15.20 |
17.46 |
241.82 |
43.60 |
41.52 |
255.86 |
28 |
15.94 |
17.96 |
242.40 |
44.20 |
42.10 |
258.24 |
R = replicate
Table 2: Percentage
biodegradation values.
Day |
Biodegradation (%) |
||||
Procedure Control |
Test Item |
ToxicityControl |
|||
R1 |
R2 |
Mean |
|||
0 |
0 |
0 |
0 |
0 |
0 |
1 |
0 |
2 |
2 |
2 |
1 |
2 |
0 |
4 |
4 |
4 |
2 |
3 |
1 |
5 |
5 |
5 |
2 |
4 |
4 |
6 |
6 |
6 |
4 |
5 |
21 |
7 |
6 |
7 |
14 |
6 |
44 |
7 |
7 |
7 |
26 |
7 |
56 |
8 |
7 |
8 |
31 |
8 |
59 |
8 |
7 |
8 |
32 |
9 |
62 |
8 |
7 |
8 |
33 |
10 |
65 |
8 |
7 |
8 |
33 |
11 |
66 |
9 |
8 |
9 |
34 |
12 |
67 |
9 |
8 |
9 |
34 |
13 |
68 |
9 |
8 |
9 |
35 |
14 |
69 |
9 |
8 |
9 |
35 |
15 |
69 |
9 |
8 |
9 |
35 |
16 |
71 |
9 |
8 |
9 |
36 |
17 |
71 |
9 |
9 |
9 |
36 |
18 |
72 |
9 |
9 |
9 |
36 |
19 |
72 |
10 |
9 |
10 |
37 |
20 |
72 |
10 |
9 |
10 |
37 |
21 |
72 |
10 |
9 |
10 |
37 |
22 |
72 |
10 |
9 |
10 |
38 |
23 |
73 |
10 |
9 |
10 |
39 |
24 |
73 |
10 |
9 |
10 |
40 |
25 |
73 |
10 |
9 |
10 |
41 |
26 |
73 |
10 |
9 |
10 |
41 |
27 |
73 |
10 |
9 |
10 |
42 |
28 |
73 |
10 |
9 |
10 |
42 |
R = replicate
Table 3: Validity criteria for OECD 301.
Criterion from the guideline |
Outcome |
Validity criterion fulfilled |
Difference of extremes of replicate values of the removal of the test chemical at the plateau, at the end of the test or at the end of the 10-d window, as appropriate, is less than 20%. |
Difference between extremes of replicate BOD values at the end of the test: < 20% |
yes |
Percentage degradation of the reference compound reached the pass level by day 14 (≥ 60%). |
69% by day 14 |
yes |
The toxicity control should degrade to at least 35% (based on DOC) or at least 25% (based on ThOD or ThCO2) within 14 d. |
5% biodegradation after 14 days and 42% biodegradation biodegradation after |
yes |
The oxygen uptake of the inoculum blank is normally 20-30 mg O2/L and should not be greater than 60 mg/L in 28 days. |
16.95 mg O2/L |
yes |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Remarks:
- For further details please refer to “Any other information on results incl. tables”.
- Interpretation of results:
- not readily biodegradable
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