Registration Dossier
Registration Dossier
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EC number: 434-770-8 | CAS number: 55314-16-4
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 10 July 2000 - 11 July 2000
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: This study has been performed according to OECD and EC guidelines and according to GLP principles.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 000
- Report date:
- 2000
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The sample is initially observed to determine whether sieving of the material is required. The final sample is the analysed using the Coulter Laser Defraction Analyser fitted with a dry powder module. It is normal practice to complete 3 runs to ensure repeatability of results.
- GLP compliance:
- yes (incl. QA statement)
- Type of distribution:
- other: Laser diffraction analysis
Test material
- Reference substance name:
- -
- EC Number:
- 434-770-8
- EC Name:
- -
- Cas Number:
- 55314-16-4
- Molecular formula:
- C10 H12 N2 O1
- IUPAC Name:
- 3-(dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one
- Details on test material:
- Identification: STI571 Y5A
Description: Brown solid
Batch: 0093800007
Purity: >95%
Test substance storage: In refrigerator in the dark
Stability under storage conditions: Not indicated
Expiry date: 08 May 2001
Constituent 1
Results and discussion
Particle sizeopen allclose all
- Percentile:
- D50
- Mean:
- 421.8 µm
- Remarks on result:
- other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.
- Percentile:
- D10
- Mean:
- 180 µm
- Percentile:
- D50
- Mean:
- 421.8 µm
- Percentile:
- D90
- Mean:
- 742 µm
Applicant's summary and conclusion
- Conclusions:
- The Particle Size Analysis produced the following results:
Volume (%): 100.0
Mean (µm): 383.8 95% Conf. Limits (µm): 122-1210
Median (µm): 421.8 S.D.: 1.79
Mode (µm): 454.6
%< 10 25 50 75 90
Size (µm) 180.0 286.0 421.8 586.3 742.0
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