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EC number: 216-885-3 | CAS number: 1689-99-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
The substance was tested on different aquatic organisms, representing the three trophic levels: fish, invertebrates and algae; furthermore, testing on microorganisms also is available. With respect to fish and aquatic organisms, data are available for both freshwater and marine water.
The 96-hour LC50 for fish exposed to the present test material was 0.041 mg a.i./L for O. mykiss in freshwater.
The 96-hour LC50 for fish exposed to the present test material was 0.170 mg a.i./L for C. variegatus in saltwater.
The 48-hour EC50 for aquatic invertebrates exposed to the present test material was 0.03 mg a.i./L for D. magna in freshwater.
The 96-hour LC50 for aquatic invertebrates exposed to the present test material was 0.087 mg a.i./L for M. bahia in saltwater.
The 120-h ErC50 for algae exposed to the present test material was 0.22 mg a.i./L for P. subcapitata in freshwater.
The NOEC for early life stage of P. promelas was 0.0049 mg a.i./L.
The 21-day NOEC for aquatic invertebrates exposed to the present test material was 0.0036 mg a.i./L for D. magna in freshwater.
The 120-h ErC10 for algae exposed to the present test material was 0.0087 mg a.i./L for P. subcapitata in freshwater.
The 3-hour EC50 for microorganisms exposed to the present test material was > 1000 mg /L.
Additional information
The substance was tested on aquatic organisms of different trophic levels (fish, invertebrates, algae, aquatic plants and activated sludge).
A short-term key toxicity study assessed the effects on fish, according to OECD 203 performed with the rainbow trout (O. mykiss, 96 h, freshwater). The acute effect value in fish was determined in with an LC50(96h) of 0.041 mg a.i./L (mean measured).
The long-term effects of the substance towards fish were examined in a flow-through 35-day early-life stage toxicity test with Pimephales promelas according to EPA OPP 72-4. A NOEC (35d) of 0.0049 mg a.i./L (mean measured) was determined as the derived chronic value.
Aquatic invertebrates were the most sensitive organisms when exposed to the test substance. In an acute toxicity test on the freshwater invertebrate (OECD 202), Daphnia magna, immobility was assessed, resulting in an EC50(48 h) of 0.03 mg a.i./L (mean measured).
The long-term effects of the substance towards Daphnia magna were examined in a 21-day toxicity test according to EPA OPP 72-4. A NOEC (21d) of 0.0036 mg a.i./L (mean measured) was determined.
The toxicity of the substance to aquatic algae was investigated in a study performed according to EPA OPP 122-2 with freshwater algae P. subcapitata. The 120-h ErC50and ErC10were 0.22 mg a.i./L and 0.0087 mg a.i./L, respectively, based on mean measured concentrations.
The effect of the substance on the respiration rate of microorganisms (activated sludge) was examined in a dose-response test. The EC50(3 h) was determined to be > 1000 mg/L (nominal). Thus, the test substance is not inhibitory to microorganisms.
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