Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2019-04-17 to 2019-05-16
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Version / remarks:
- 1992
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 52.03 mg/L
- Based on:
- ThOD
- Initial conc.:
- 28.91 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Test item vessels containing test item with a concentration of 28.91 mg test item /L (2 replicates);
Process control vessels containing reference item with a concentration of 31.25 mg reference item /L (2 replicates);
Toxicity control vessels containing test item with a concentration of 28.96 mg test item /L and reference item with a concentration of 31.63(1 replicate);
Blank control vessels containing only inoculated mineral medium without test item (2 replicates). - Reference substance:
- benzoic acid, sodium salt
- Preliminary study:
- No
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 74
- Sampling time:
- 28 d
- Results with reference substance:
- Biodegradation of the reference substance reached 60% after 4 days, 84.8% after 28 days.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The test item was readily biodegradable.
- Executive summary:
The ready biodegradability of the test item was performed according to OECD guideline 301F (manometric respirometry test) and GLP. The test was conducted with unacclimatised sewage microorganism by measuring oxgen consumption over a 28-day test period. The test concentration was set at 28.91 mg test item/L (equivalent to 52.03 mg/L as Theoretical Oxygen Demand). Sodium benzoate was used as positive reference substance. The test item was not inhibitory to microorganism under the conditions of this test. The percentage biodegradation of the test item over 28 days was 74.0% and the 10-day window was met (5-15 day).The test item was determined to be readily biodegradable under test conditions.
Reference
Description of key information
A study of the ready biodegradability of the test item was performed according to OECD guideline 301F (manometric respirometry test) and GLP. The test was conducted with unacclimatised sewage microorganism by measuring oxgen consumption over a 28-day test period. The test concentration was set at 28.91 mg test item/L (equivalent to 52.03 mg/L as Theoretical Oxygen Demand). Sodium benzoate was used as positive reference substance. The test item was not inhibitory to microorganism under the conditions of this test. The percentage biodegradation of the test item over 28 days was 74.0% and the 10-day window was met (5-15 day).The test item was determined to be readily biodegradable under test conditions.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.