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EC number: 814-970-5 | CAS number: 852620-97-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2020-12-18 to 2021-02-19
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Freshwater Alga and Cyanobacteria, Growth Inhibition Test)
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- yes
- Details on sampling:
- See attached report
- Vehicle:
- no
- Test organisms (species):
- Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum)
- Details on test organisms:
- The Pseudokirchneriella subcapitata stock culture was maintained at 4°C and regularly transferred to fresh medium at the laboratory. The algal stock culture was provided by the CCAP (Culture Collection of Algae and Protozoa), reference CCAP 278/4.
A pre-culture was prepared from the stock culture and maintained in an exponential growth by successive transfers to fresh medium used in the test (OECD medium) every 3 to 4 days. To ensure that the algae are in the exponential growth phase when used to inoculate the test solutions, an inoculum culture in the test medium was prepared 3 days before start of the test. - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 72 h
- Test temperature:
- 23 to 23.7°C
- pH:
- 7.7 to 8.1
- Nominal and measured concentrations:
- Nominal: 0; 6.25; 12.5; 25.0; 50.0; 100 mg/L
- Reference substance (positive control):
- yes
- Remarks:
- potassium dichromate
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Key result
- Duration:
- 72 h
- Dose descriptor:
- EC10
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Validity criteria fulfilled:
- yes
- Conclusions:
- Under the conditions of an experimental study performed according to OECD 201 guideline and under GLP conditions, the substance exhibits EC50 and EC10 above 100 mg/L on the growth of Pseudokirchneriella subcapitata over a period of 72 hours.
- Executive summary:
The objective of this study was to assess the effects of test item N-Propyl-N-methylpyrrolidinium Bis(fluorosulfonyl)imide on the growth of Pseudokirchneriella subcapitata over a period of 72 hours according to OECD 201 Guideline. Pseudokirchneriella subcapitata is a freshwater green algae that is recommended by the OECD Guideline 201 (2006, corrected 2011).
The test item is a soluble product under the test conditions and the test solutions were prepared in the test medium by dilution of a primary stock solution of test item.
The effects of N-Propyl-N-methylpyrrolidinium Bis(fluorosulfonyl)imide at the definitive nominal concentrations of 0; 6.25; 12.5; 25.0; 50.0 and 100 mg test item.L-1 to Pseudokirchneriella subcapitata were investigated under laboratory static conditions.
The analytical samples were sampled at the beginning of the test and at the end of the test (72 hours) with the content of the vessels pooled and homogenized. Since the deviations between the measured concentrations and the nominal concentrations were within the range of ± 20 %, analysis of the results was based on the nominal concentrations.
The results are the following:
NOEC (growth rate): 100 mg/L
LOEC (growth rate): > 100 mg/L
NOEC (yield): 100 mg/L
LOEC (yield): > 100 mg/L
72h-ErC10: > 100 mg/L
72h-ErC20: > 100 mg/L
72h-ErC50: > 100 mg/L
72h-EyC10: > 100 mg/L
72h-EyC20: > 100 mg/L
72h-EyC50: > 100 mg/L
Reference
Description of key information
Under the conditions of an experimental study performed according to OECD 201 guideline and under GLP conditions, the substance exhibits EC50 and EC10 above 100 mg/L on the growth of Pseudokirchneriella subcapitata over a period of 72 hours.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 100 mg/L
- EC10 or NOEC for freshwater algae:
- 100 mg/L
Additional information
The validity criteria of the study are met. Therefore, we can consider this study valid and acceptable for that endpoint.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.