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EC number: 203-867-5 | CAS number: 111-41-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 31 March 2020 - 01 May 2020
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Reference
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 31 March 2020 - 01 May 2020
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Version / remarks:
- 2016
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling Point)
- Version / remarks:
- 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
- Version / remarks:
- 1996
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- differential scanning calorimetry
- Key result
- Decomp. temp.:
- °C
- Remarks on result:
- other: No boiling up to decomposition.
- Conclusions:
- Boiling of the substance was not observed below the temperature at which reaction and/or decomposition started (i.e. at 200°C).
- Executive summary:
see IUCLID 4.2 melting point
see IUCLID 4.2 melting point
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 020
- Report date:
- 2020
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Version / remarks:
- 2016
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Version / remarks:
- 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7200 (Melting Point / Melting Range)
- Version / remarks:
- 1998
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- differential scanning calorimetry
Test material
- Reference substance name:
- 2-(2-aminoethylamino)ethanol
- EC Number:
- 203-867-5
- EC Name:
- 2-(2-aminoethylamino)ethanol
- Cas Number:
- 111-41-1
- Molecular formula:
- C4H12N2O
- IUPAC Name:
- 2-[(2-aminoethyl)amino]ethan-1-ol
- Test material form:
- liquid: viscous
- Details on test material:
- Physical Description: Colourless viscous liquid
Purity/Composition correction factor: No correction factor require
Storage Conditions: At room temperature protected from light container flushed with nitrogen
Test item handling: Use amber glassware or wrap container in aluminum foil
Constituent 1
Results and discussion
Melting / freezing point
- Key result
- Remarks on result:
- other: Glass transition point: -76.7°C. No melting/freezing temperature between 25°C and -90°C.
Any other information on results incl. tables
TGA EXPERIMENT (PRELIMINARY TEST)
The weight of the sample decreased significantly at temperatures above 200°C: 25% decrease at 223°C and 70% decarease at 271°C.
Appearance of the sample after the experiment: yellow molten residue remained in the sample container (original colour: colourless).
The change of colour is an indicator for reaction and/or decomposition of the test item.
DSC EXPERIMENT 1
During cooling, a glass transition effect between -60°C and -90°C was found.
During heating a glass transition effect was observed between -90°C and -50°C. Between 100°C and 175°C an broad endothermic followed by a strong exothermic effect was observed starting at 200°C. The inflection point of the glass transition was -76.702°C. The endothermic effect was most likely obtained due to the evaporation of impurities of the test item. The exothermic effect was probably obtained due to reaction and/or decomposition of the test item.
DSC EXPERIMENT 2
Experiment 2 was performed as a duplicate of Experiment 1, only the end temperature was 25°C instead of 223°C.
Similar results as in Experiment 1 were obtained. The inflection point of the glass transition was -76.732°C.
After the experiment, the residue remained in the sample container was unchanged.
DSC curve: see illustration below.
RESULT
The glass transition temperature: determined as the mean inflection point of Experiment 1 (-76.702°C) and Experiment 2 (-76.732°C).
Boiling temperature: the substance has no boiling temperature. Reaction and/or decomposition of the test item was observed during DSC experiments starting at 200°C (473K). Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started.
Applicant's summary and conclusion
- Conclusions:
- A glass transition temperature of -76.7°C was determined. The substance has no melting/freezing temperature between 25°C and -90°C.
- Executive summary:
The melting and boiling temperature of the test item were determined in a GLP study using Differential Scanning Calorimetry (DSC).
The experiments were in accordance with EC A.1, OECD 102 and OPPTS 830.7200 (melting temperature) and EC A.2, OECD TG 103 and OPPTS 830.722 (boiling temperature).
A glass transition effect was observed between -90°C and -50°C. Between 100°C and 175°C an broad endothermic, followed by a strong exothermic effect was observed starting at 200°C. The endothermic effect was most likely obtained due to the evaporation of impurities of the test item. The exothermic effect was probably obtained due to reaction and/or decomposition of the test item.
The liquid substance has no melting/freezing temperature between 25°C and -90°C. From duplicate measurements the mean glass transition temperature was determined to be -76.7°C.
Boiling of the substance was not observed below the temperature at which reaction and/or decomposition started (i.e. at 200°C). It was concluded that the substance has no boiling temperature.
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