Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 952-948-8 | CAS number: -
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 08 November 2019 to 17 February 2020
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- 1995
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- 2014
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Specific details on test material used for the study:
- Purity: 94.5 %
Storage Condition: Ambient temperature, cool and dry conditions, DEFITRACES. - Key result
- Water solubility:
- 871 mg/L
- Conc. based on:
- test mat. (dissolved fraction)
- Incubation duration:
- 72 h
- Temp.:
- 30 °C
- pH:
- 4
- Key result
- Water solubility:
- 856 mg/L
- Conc. based on:
- test mat. (dissolved fraction)
- Incubation duration:
- 72 h
- Temp.:
- 30 °C
- pH:
- 7
- Key result
- Water solubility:
- 881 mg/L
- Conc. based on:
- test mat. (dissolved fraction)
- Incubation duration:
- 72 h
- Temp.:
- 30 °C
- pH:
- 9
- Conclusions:
- Using the flask method it was shown that the solubility of 3-Bromo-1-(3-Chloro-2-Pyridyl)-5-Methyl-1H-Pyrazole shows no significant pH dependance ranging from 871 mg/L (pH = 4) to 881 mg/L (pH = 9).
- Executive summary:
The objective of this study is to determine the solubility in water of 3-Bromo-1-(3-Chloro-2-Pyridyl)-5-Methyl-1H-Pyrazole following the Regulation (EC) No.1907/2006 - and Council regulation (EC) No. 260/2014 - EC A.6. method (2014) and OECD Guideline No. 105 (1995).
The solubility of 3-Bromo-1-(3-Chloro-2-Pyridyl)-5-Methyl-1H-Pyrazole in water performed at three pH (4, 7 and 9) was as followed:
pH (4) = 871 mg/L
pH(7) = 856 mg/L
pH (9) = 881 mg/L
Reference
Description of key information
The objective of this study is to determine the solubility in water of 3-Bromo-1-(3-Chloro-2-Pyridyl)-5-Methyl-1H-Pyrazole following the Regulation (EC) No.1907/2006 - and Council regulation (EC) No. 260/2014 - EC A.6. method (2014) and OECD Guideline No. 105 (1995).
The solubility of 3-Bromo-1-(3-Chloro-2-Pyridyl)-5-Methyl-1H-Pyrazole in water performed at three pH (4, 7 and 9) was as followed:
pH (4) = 871 mg/L
pH(7) = 856 mg/L
pH (9) = 881 mg/L
Key value for chemical safety assessment
- Water solubility:
- 856 mg/L
- at the temperature of:
- 30 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
