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EC number: 941-634-6 | CAS number: 1228284-78-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2015-04-17 until 2015-07-24
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study conducted in accordance with current guidelines and GLP compliance.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
- Name of test material (as cited in study report): CA5204A (MOAT)
- Physical state: Brown liquid
- Analytical purity: 93.2 %
- Lot/batch No.: SMU2DP12003
- Recertification date of the lot/batch: End of September 2015
- ThOD: 1.444 g O2/g considering total nitrification; 1.222 g O2/g considering no nitrification - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): sewage treatment plant
Ruhrverband Kläranlage, Sunthelle 6, 57392 Schmallenberg, Germany
- Date of sampling: 28th April 2015
- Storage conditions: No storage
- Preparation of inoculum for exposure: No washing, the concentration was adjusted to 3.0 g/L and verified by dry mass
measurement.
- Pretreatment: Kept aerobic until use
- Concentration of sludge in the test: 29.6 mg dry mass/litre - Duration of test (contact time):
- 28 d
- Initial conc.:
- 44 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Remarks:
- (63.5 mg ThOD considering total nitrification and 53.7 mg ThOD considering the total lack of nitrification.)
- Details on study design:
- - The concentration in the test assays were 44 mg per litre mineral test medium (11 mg/250 mL). 44 mg test item correspond to 63.5 mg ThOD considering total nitrification and 53.7 mg ThOD considering the total lack of nitrification. The required amount of test item was added directly on a weight basis via Teflon discs. Subsequently, the required volume of aqueous reference stock solution and mineral medium were added to the vessels.
- The concentration in the test vessels with reference item (procedural control, toxicity control) was 100 mg per litre mineral test
medium (25 mg/250 mL).
- A further solution containing both test and reference item at the same concentrations as in the individual solutions (test item 44 mg/L, reference item 100 mg/L) was prepared to determine the possible toxicity of the test item against the inoculum.
- Further flasks with mineral medium only were prepared for inoculum controls.
- Abiotic controls were also prepared to measure any possible abiotic degradation; a solution of the test item at about 44 mg/L was sterilized by the addition of 1 mL/L HgCl2 (10 g/L).
- In all test assays except of the abiotic controls, 2.49 mL of the inoculum stock solution were transferred for inoculation (per 250 mL) resulting in a concentration of 29.6 mg dry mass/litre (7.40 mg dry mass/250 mL). - Reference substance:
- benzoic acid, sodium salt
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 28 d
- Results with reference substance:
- The reference item was degraded by an average of 89 % by Exposure Day 14, thus confirming suitability of the activated sludge. At the end of the test (Day 28), the reference item was degraded by an average of 102 %.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The biochemical oxygen demand (BOD) of the test item in the test media was in the range of the inoculum controls throughout the
study period of 28 days. Consequently, the test item was not biodegradable under the test conditions within 28 days. - Executive summary:
At the Fraunhofer Institute for Molecular Biology and Applied Ecology the ready biodegradability of the test item was investigated according to the manometric respirometry test design and carried out according to the OECD guideline for Testing of Chemicals No. 301 F (1992) and the Council Regulation (EC) No 440/2008 of 30 May 2008.
The ready biodegradability of the test item was investigated at a concentration of 44 mg/L in a manometric respirometry test using domestic aerobic activated sewage sludge incubated at 22°C in the dark over 28 days under continuous stirring. The biochemical oxygen demand (BOD) was measured daily and the percentage degradation was calculated from the theoretical oxygen demand (ThOD) after correcting for the BOD of inoculum controls.
The biochemical oxygen demand of the test item in the test media was in the same range as the inoculum controls, so the test item exhibited no significant additional oxygen demand. Consequently, the test itemwas not biodegradable under the conditions of the test. The test item had no inhibitory effect on the activity of activated sludge microorganisms at the tested concentration. In the procedural controls, the reference substance sodium benzoate was degraded by an average of 89 % by exposure day 14, and reached an average biodegradation of 102 % by the end of the test (day 28), thus confirming suitability of the activated sludge.
Reference
Results are provided in the attached document.
Description of key information
The biochemical oxygen demand (BOD) of the test item in the test media was in the range of the inoculum controls throughout the
study period of 28 days. Consequently, the test item was not biodegradable under the test conditions within 28 days.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
- Type of water:
- freshwater
Additional information
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